[HTML][HTML] Biomedical applications of microfluidic devices: a review

G Gharib, İ Bütün, Z Muganlı, G Kozalak, İ Namlı… - Biosensors, 2022 - mdpi.com
Both passive and active microfluidic chips are used in many biomedical and chemical
applications to support fluid mixing, particle manipulations, and signal detection. Passive …

Compartmentalizing cell-free systems: toward creating life-like artificial cells and beyond

E Cho, Y Lu - ACS Synthetic Biology, 2020 - ACS Publications
Building an artificial cell is a research area that is rigorously studied in the field of synthetic
biology. It has brought about much attention with the aim of ultimately constructing a natural …

Droplet microfluidics for synthetic biology

PC Gach, K Iwai, PW Kim, NJ Hillson, AK Singh - Lab on a Chip, 2017 - pubs.rsc.org
Synthetic biology is an interdisciplinary field that aims to engineer biological systems for
useful purposes. Organism engineering often requires the optimization of individual genes …

Cell-sized mechanosensitive and biosensing compartment programmed with DNA

S Majumder, J Garamella, YL Wang… - Chemical …, 2017 - pubs.rsc.org
The bottom-up construction of cell-sized compartments programmed with DNA that are
capable of sensing the chemical and physical environment remains challenging in synthetic …

New advances in probing cell–extracellular matrix interactions

AP Liu, O Chaudhuri, SH Parekh - Integrative Biology, 2017 - academic.oup.com
The extracellular matrix (ECM) provides structural and biochemical support to cells within
tissues. An emerging body of evidence has established that the ECM plays a key role in cell …

Microfluidics for artificial life: techniques for bottom-up synthetic biology

P Supramaniam, O Ces, A Salehi-Reyhani - Micromachines, 2019 - mdpi.com
Synthetic biology is a rapidly growing multidisciplinary branch of science that exploits the
advancement of molecular and cellular biology. Conventional modification of pre-existing …

Recent advances of droplet-based microfluidics for engineering artificial cells

S Fasciano, S Wang - SLAS technology, 2024 - Elsevier
Artificial cells, synthetic cells, or minimal cells are microengineered cell-like structures that
mimic the biological functions of cells. Artificial cells are typically biological or polymeric …

Pressure-driven flow through PDMS-based flexible microchannels and their applications in microfluidics

A Raj, PPA Suthanthiraraj, AK Sen - Microfluidics and Nanofluidics, 2018 - Springer
Flexible microchannels have soft walls which undergo deformation under the influence of
fluid flow. The dimensional and flexural similarity of flexible microchannels make them ideal …

[HTML][HTML] Screening and selection of cellulase-secreting yeast single cells using integrated double emulsion droplet and flow cytometry techniques

H Liu, Y Zhang, H Kroukamp, K Peng, AK Cain… - Sensors and Actuators B …, 2024 - Elsevier
The capability of yeast cell factories to secrete industrially important enzymes into the
extracellular environment can significantly reduce overall production costs. This impacts a …

Electric field modulated deformation dynamics of a compound drop in the presence of confined shear flow

S Santra, A Jana, S Chakraborty - Physics of Fluids, 2020 - pubs.aip.org
Dynamics of compound drops is central in several emerging applications including emulsion-
fueled direct injection, targeted drug delivery, and the development of mechano-sensitive …