Thermal immuno-nanomedicine in cancer

Z Yang, D Gao, J Zhao, G Yang, M Guo… - Nature Reviews …, 2023‏ - nature.com
Immunotherapy has revolutionized the treatment of patients with cancer. However,
promoting antitumour immunity in patients with tumours that are resistant to these therapies …

Magnetic nanoparticles and clusters for magnetic hyperthermia: Optimizing their heat performance and develo** combinatorial therapies to tackle cancer

H Gavilán, SK Avugadda… - Chemical Society …, 2021‏ - pubs.rsc.org
Magnetic hyperthermia (MHT) is a therapeutic modality for the treatment of solid tumors that
has now accumulated more than 30 years of experience. In the ongoing MHT clinical trials …

Turning cold tumors into hot tumors by improving T-cell infiltration

YT Liu, ZJ Sun - Theranostics, 2021‏ - pmc.ncbi.nlm.nih.gov
Immunotherapy, represented by immune checkpoint inhibitors (ICIs), has greatly improved
the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend …

Bioorthogonal chemistry for prodrug activation in vivo

Q Fu, S Shen, P Sun, Z Gu, Y Bai, X Wang… - Chemical Society …, 2023‏ - pubs.rsc.org
Prodrugs have emerged as a major strategy for addressing clinical challenges by improving
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …

[HTML][HTML] Biomedical applications of metallic nanoparticles in cancer: Current status and future perspectives

R Khursheed, K Dua, S Vishwas, M Gulati… - Biomedicine & …, 2022‏ - Elsevier
The current advancements in nanotechnology are as an outcome of the development of
engineered nanoparticles. Various metallic nanoparticles have been extensively explored …

Stimuli‐responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy

J Zhang, Y Lin, Z Lin, Q Wei, J Qian, R Ruan… - Advanced …, 2022‏ - Wiley Online Library
Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

Metallo-alginate hydrogel can potentiate microwave tumor ablation for synergistic cancer treatment

Y Zhu, Z Yang, Z Pan, Y Hao, C Wang, Z Dong, Q Li… - Science …, 2022‏ - science.org
Microwave ablation (MWA) as a local tumor ablation strategy suffers from posttreatment
tumor recurrence. Development of adjuvant biomaterials to potentiate MWA is therefore of …

Comprehensive understanding of magnetic hyperthermia for improving antitumor therapeutic efficacy

X Liu, Y Zhang, Y Wang, W Zhu, G Li, X Ma… - …, 2020‏ - pmc.ncbi.nlm.nih.gov
Magnetic hyperthermia (MH) has been introduced clinically as an alternative approach for
the focal treatment of tumors. MH utilizes the heat generated by the magnetic nanoparticles …

Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021‏ - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

Janus nanoparticles: From fabrication to (bio) applications

X Zhang, Q Fu, H Duan, J Song, H Yang - ACS nano, 2021‏ - ACS Publications
Janus nanoparticles (JNPs) refer to the integration of two or more chemically discrepant
composites into one structure system. Studies into JNPs have been of significant interest …