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Host entry by gamma-herpesviruses—lessons from animal viruses?
L Gillet, B Frederico, PG Stevenson - Current opinion in virology, 2015 - Elsevier
Highlights•There is no good evidence for oral gammaherpesvirus entry.•Animal viruses can
help us to decipher their human counterparts.•MuHV-4 enters new hosts via the olfactory …
help us to decipher their human counterparts.•MuHV-4 enters new hosts via the olfactory …
Macrophages drive KSHV B cell latency
A Szymula, G Samayoa-Reyes, S Ogolla, B Liu, S Li… - Cell reports, 2023 - cell.com
Kaposi's sarcoma herpesvirus (KSHV) establishes lifelong infection and persists in latently
infected B cells. Paradoxically, in vitro B cell infection is inefficient, and cells rapidly die …
infected B cells. Paradoxically, in vitro B cell infection is inefficient, and cells rapidly die …
Interplay of murine gammaherpesvirus 68 with NF-kappaB signaling of the host
B Cieniewicz, AL Santana, N Minkah… - Frontiers in …, 2016 - frontiersin.org
Herpesviruses establish a chronic infection in the host characterized by intervals of lytic
replication, quiescent latency, and reactivation from latency. Murine gammaherpesvirus 68 …
replication, quiescent latency, and reactivation from latency. Murine gammaherpesvirus 68 …
Murine cytomegalovirus exploits olfaction to enter new hosts
Viruses transmit via the environmental and social interactions of their hosts. Herpesviruses
have colonized mammals since their earliest origins, suggesting that they exploit ancient …
have colonized mammals since their earliest origins, suggesting that they exploit ancient …
A murid gamma-herpesviruses exploits normal splenic immune communication routes for systemic spread
B Frederico, B Chao, JS May, GT Belz, PG Stevenson - Cell host & microbe, 2014 - cell.com
Gamma-herpesviruses (γHVs) are widespread oncogenic pathogens that chronically infect
circulating lymphocytes. How they subvert the immune check-point function of the spleen to …
circulating lymphocytes. How they subvert the immune check-point function of the spleen to …
Indirect CD4+ T cell protection against mouse gamma-herpesvirus infection via interferon gamma
ABSTRACT CD4+ T cells play a key role in γ-herpesvirus infection control. However, the
mechanisms involved are unclear. Murine herpesvirus type 4 (MuHV-4) allows relevant …
mechanisms involved are unclear. Murine herpesvirus type 4 (MuHV-4) allows relevant …
Glycoprotein K8. 1A of Kaposi's sarcoma-associated herpesvirus is a critical B cell tropism determinant independent of its heparan sulfate binding activity
SJ Dollery, RJ Santiago-Crespo, D Chatterjee… - Journal of …, 2019 - journals.asm.org
ABSTRACT B lymphocytes are the major cellular reservoir in individuals infected with
Kaposi's sarcoma-associated herpesvirus (KSHV), and the virus is etiologically linked to two …
Kaposi's sarcoma-associated herpesvirus (KSHV), and the virus is etiologically linked to two …
A gammaherpesvirus noncoding RNA is essential for hematogenous dissemination and establishment of peripheral latency
Recent intense investigations have uncovered important functions for a diverse array of
novel noncoding RNA (ncRNA) species, including microRNAs (miRNAs) and long …
novel noncoding RNA (ncRNA) species, including microRNAs (miRNAs) and long …
Alveolar macrophages are a prominent but nonessential target for murine cytomegalovirus infecting the lungs
HE Farrell, C Lawler, MT Oliveira… - Journal of …, 2016 - journals.asm.org
Cytomegaloviruses (CMVs) infect the lungs and cause pathological damage there in
immunocompromised hosts. How lung infection starts is unknown. Inhaled murine CMV …
immunocompromised hosts. How lung infection starts is unknown. Inhaled murine CMV …
Engineered commensals for targeted nose-to-brain drug delivery
Intranasal administration through the olfactory epithelium (OE) presents a direct pathway for
brain-targeted therapeutic delivery, although its feasibility is hampered by the anatomical …
brain-targeted therapeutic delivery, although its feasibility is hampered by the anatomical …