Neurodegenerative and neurodevelopmental diseases and the gut-brain axis: the potential of therapeutic targeting of the microbiome

B Bicknell, A Liebert, T Borody, G Herkes… - International journal of …, 2023 - mdpi.com
The human gut microbiome contains the largest number of bacteria in the body and has the
potential to greatly influence metabolism, not only locally but also systemically. There is an …

[HTML][HTML] The microbiota in cirrhosis and its role in hepatic decompensation

J Trebicka, J Macnaughtan, B Schnabl… - Journal of …, 2021 - Elsevier
Cirrhosis–the common end-stage of chronic liver disease–is associated with a cascade of
events, of which intestinal bacterial overgrowth and dysbiosis are central. Bacterial toxins …

Rifaximin-mediated gut microbiota regulation modulates the function of microglia and protects against CUMS-induced depression-like behaviors in adolescent rat

H Li, Y **ang, Z Zhu, W Wang, Z Jiang, M Zhao… - Journal of …, 2021 - Springer
Background Chronic unpredictable mild stress (CUMS) can not only lead to depression-like
behavior but also change the composition of the gut microbiome. Regulating the gut …

Colonic diverticular disease

A Tursi, C Scarpignato, LL Strate, A Lanas… - Nature Reviews …, 2020 - nature.com
Diverticula are outpouchings of the intestinal wall and are common anatomical alterations
detected in the human colon. Colonic diverticulosis (the presence of diverticula in the colon; …

Gut microbiota modulation in patients with non-alcoholic fatty liver disease: Effects of current treatments and future strategies

M Maestri, F Santopaolo, M Pompili, A Gasbarrini… - Frontiers in …, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is frequently associated with metabolic disorders,
being highly prevalent in obese and diabetic patients. Many concomitant factors that …

[HTML][HTML] New insights into the pathogenesis of non-alcoholic fatty liver disease: gut-derived lipopolysaccharides and oxidative stress

D Ferro, F Baratta, D Pastori, N Cocomello, A Colantoni… - Nutrients, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide. The intricate NAFLD pathogenesis is summarized by the multiple-hits …

Metabolic influences of gut microbiota dysbiosis on inflammatory bowel disease

S Sultan, M El-Mowafy, A Elgaml, TAE Ahmed… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel diseases (IBD) are chronic medical disorders characterized by recurrent
gastrointestinal inflammation. While the etiology of IBD is still unknown, the pathogenesis of …

Microbiome as a therapeutic target in alcohol-related liver disease

SK Sarin, A Pande, B Schnabl - Journal of hepatology, 2019 - Elsevier
Alcohol-related liver disease is associated with significant changes in gut microbial
composition. The transmissibility of ethanol-induced liver disease has been demonstrated …

Exploring the gut microbiota: lifestyle choices, disease associations, and personal genomics

S Pedroza Matute, S Iyavoo - Frontiers in Nutrition, 2023 - frontiersin.org
The gut microbiota is a rich and dynamic ecosystem that actively interacts with the human
body, playing a significant role in the state of health and disease of the host. Diet, exercise …

Intestinal microbiome and NAFLD: molecular insights and therapeutic perspectives

H Hu, A Lin, M Kong, X Yao, M Yin, H **a, J Ma… - Journal of …, 2020 - Springer
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of dysregulated lipid
and glucose metabolism, which is often associated with obesity, dyslipidemia and insulin …