How do the brain's time and space mediate consciousness and its different dimensions? Temporo-spatial theory of consciousness (TTC)
Time and space are the basic building blocks of nature. As a unique existent in nature, our
brain exists in time and takes up space. The brain's activity itself also constitutes and …
brain exists in time and takes up space. The brain's activity itself also constitutes and …
Human neural correlates of sevoflurane-induced unconsciousness
Sevoflurane, a volatile anaesthetic agent well-tolerated for inhalation induction, provides a
useful opportunity to elucidate the processes whereby halogenated ethers disrupt …
useful opportunity to elucidate the processes whereby halogenated ethers disrupt …
The ageing brain: age-dependent changes in the electroencephalogram during propofol and sevoflurane general anaesthesia
Background Anaesthetic drugs act at sites within the brain that undergo profound changes
during typical ageing. We postulated that anaesthesia-induced brain dynamics observed in …
during typical ageing. We postulated that anaesthesia-induced brain dynamics observed in …
Mechanical failure modes of chronically implanted planar silicon-based neural probes for laminar recording
Penetrating intracortical electrode arrays that record brain activity longitudinally are powerful
tools for basic neuroscience research and emerging clinical applications. However …
tools for basic neuroscience research and emerging clinical applications. However …
Thalamocortical synchronization during induction and emergence from propofol-induced unconsciousness
FJ Flores, KE Hartnack, AB Fath… - Proceedings of the …, 2017 - National Acad Sciences
General anesthesia (GA) is a reversible drug-induced state of altered arousal required for
more than 60,000 surgical procedures each day in the United States alone. Sedation and …
more than 60,000 surgical procedures each day in the United States alone. Sedation and …
Sleep–wake cycle in young and older mice
Sleep plays a key role in multiple cognitive functions and sleep pattern changes with aging.
Human studies revealed that aging decreases sleep efficiency and reduces the total sleep …
Human studies revealed that aging decreases sleep efficiency and reduces the total sleep …
Multi-scale, multi-modal analysis uncovers complex relationship at the brain tissue-implant neural interface: new emphasis on the biological interface
Objective. Implantable neural electrode devices are important tools for neuroscience
research and have an increasing range of clinical applications. However, the intricacies of …
research and have an increasing range of clinical applications. However, the intricacies of …
Brain connectivity dissociates responsiveness from drug exposure during propofol-induced transitions of consciousness
S Chennu, S O'Connor, R Adapa… - PLoS computational …, 2016 - journals.plos.org
Accurately measuring the neural correlates of consciousness is a grand challenge for
neuroscience. Despite theoretical advances, develo** reliable brain measures to track the …
neuroscience. Despite theoretical advances, develo** reliable brain measures to track the …
Modulatory dynamics mark the transition between anesthetic states of unconsciousness
E Adam, O Kwon, KA Montejo… - Proceedings of the …, 2023 - National Acad Sciences
Unconsciousness maintained by GABAergic anesthetics, such as propofol and sevoflurane,
is characterized by slow-delta oscillations (0.3 to 4 Hz) and alpha oscillations (8 to 14 Hz) …
is characterized by slow-delta oscillations (0.3 to 4 Hz) and alpha oscillations (8 to 14 Hz) …
Frontal alpha-delta EEG does not preclude volitional response during anaesthesia: prospective cohort study of the isolated forearm technique
Background The isolated forearm test (IFT) is the gold standard test of connected
consciousness (awareness of the environment) during anaesthesia. The frontal alpha-delta …
consciousness (awareness of the environment) during anaesthesia. The frontal alpha-delta …