Increased use of reconstruction procedures in orthopedics, due to trauma, tumor, deformity,
degeneration and an aging population, has caused a blossom, not only in surgical …

Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …

Calcium phosphate cements (CPCs) are frequently used to repair bone defects. Since their
discovery in the 1980s, extensive research has been conducted to improve their properties …

Over the last 4 decades innovations in biomaterials and medical technology have had a
sustainable impact on the development of biopolymers, titanium/stainless steel and …

Embryogenic developmental processes involve a tightly controlled regulation between
mechanical forces and biochemical cues such as growth factors, matrix proteins, and …

Tissue engineering is promising to meet the increasing need for bone regeneration.
Nanostructured calcium phosphate (CaP) biomaterials/scaffolds are of special interest as …

Bioceramics have been used for the replacement and repair of damaged hard tissues for
about 50 years, in which the mechanical properties and biocompatibility of the materials are …

The field of bioinorganics is well established in the development of a variety of therapies.
However, their application to bone regeneration, specifically by way of localized delivery …

Calcium oxalate (CaOx) kidney stones are formed attached to Randall's plaques (RPs) or
Randall's plugs. Mechanisms involved in the formation and growth are poorly understood. It …

Calcium phosphate bio-ceramics are osteo-conductive, but it remains a challenge to
promote the induction of bone augmentation and capillary formation. The surface …