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Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine
J Wen, GP Mercado, A Volland, HL Doden… - Science …, 2021 - science.org
Bile salt synthesis, secretion into the intestinal lumen, and resorption in the ileum occur in all
vertebrate classes. In mammals, bile salt composition is determined by host and microbial …
vertebrate classes. In mammals, bile salt composition is determined by host and microbial …
A nanocomposite consisting of graphene oxide, zeolite imidazolate framework 8, and a molecularly imprinted polymer for (multiple) fiber solid phase microextraction of …
A method is described for multiple monolithic fiber solid-phase microextraction of five sterol
and steroid hormones from complex food samples. A composite was prepared from …
and steroid hormones from complex food samples. A composite was prepared from …
Tebuconazole disrupts steroidogenesis in Xenopus laevis
A 27-day controlled exposure study of adult male African clawed frogs (Xenopus laevis) was
conducted to examine the mechanism by which tebuconazole may disrupt steroidogenesis …
conducted to examine the mechanism by which tebuconazole may disrupt steroidogenesis …
Development of a multi-class steroid hormone screening method using Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Monitoring complex endocrine pathways is often limited by indirect measurement or
measurement of a single hormone class per analysis. There is a burgeoning need to …
measurement of a single hormone class per analysis. There is a burgeoning need to …
High-throughput H295R steroidogenesis assay: utility as an alternative and a statistical approach to characterize effects on steroidogenesis
Abstract The US Environmental Protection Agency Endocrine Disruptor Screening Program
and the Organization for Economic Co-operation and Development (OECD) have used the …
and the Organization for Economic Co-operation and Development (OECD) have used the …
Multiplexed steroid profiling of gluco-and mineralocorticoids pathways using a liquid chromatography tandem mass spectrometry method
S Travers, L Martinerie, C Bouvattier, P Boileau… - The Journal of steroid …, 2017 - Elsevier
Serum steroid assays are major tools in the clinical evaluation of adrenal disorders. The
main adrenal steroids are routinely measured with immunoassays. However …
main adrenal steroids are routinely measured with immunoassays. However …
High-throughput screening of chemical effects on steroidogenesis using H295R human adrenocortical carcinoma cells
Disruption of steroidogenesis by environmental chemicals can result in altered hormone
levels causing adverse reproductive and developmental effects. A high-throughput assay …
levels causing adverse reproductive and developmental effects. A high-throughput assay …
Two simple cleanup methods combined with LC-MS/MS for quantification of steroid hormones in in vivo and in vitro assays
JJ Weisser, CH Hansen, R Poulsen, LW Larsen… - Analytical and …, 2016 - Springer
Measuring both progestagens, androgens, corticosteroids as well as estrogens with a single
method makes it possible to investigate the effects of endocrine-disrupting chemicals …
method makes it possible to investigate the effects of endocrine-disrupting chemicals …
LC-MS/MS based profiling and dynamic modelling of the steroidogenesis pathway in adrenocarcinoma H295R cells
KEM Ahmed, HG Frøysa, OA Karlsen, JV Sagen… - Toxicology in Vitro, 2018 - Elsevier
Endocrine disrupting chemicals have been reported to exert effects directly on enzymes
involved in steroid biosynthesis. Here, we present a new liquid chromatography-tandem …
involved in steroid biosynthesis. Here, we present a new liquid chromatography-tandem …
Steroidomic footprinting based on ultra-high performance liquid chromatography coupled with qualitative and quantitative high-resolution mass spectrometry for the …
D Tonoli, C Fürstenberger, J Boccard… - Chemical research in …, 2015 - ACS Publications
The screening of endocrine disrupting chemicals (EDCs) that may alter steroidogenesis
represents a highly important field mainly due to the numerous pathologies, such as cancer …
represents a highly important field mainly due to the numerous pathologies, such as cancer …