Stem cells in the central nervous system
R McKay - Science, 1997 - science.org
In the vertebrate central nervous system, multipotential cells have been identified in vitro and
in vivo. Defined mitogens cause the proliferation of multipotential cells in vitro, the …
in vivo. Defined mitogens cause the proliferation of multipotential cells in vitro, the …
[HTML][HTML] Niches that regulate stem cells and hematopoiesis in adult bone marrow
S Comazzetto, B Shen, SJ Morrison - Developmental cell, 2021 - cell.com
In mammals, hematopoietic stem cells (HSCs) engage in hematopoiesis throughout adult
life within the bone marrow, where they produce the mature cells necessary to maintain …
life within the bone marrow, where they produce the mature cells necessary to maintain …
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
The glucocorticoid receptor (Gr, encoded by the gene Grl1) controls transcription of target
genes both directly by interaction with DNA regulatory elements and indirectly by cross-talk …
genes both directly by interaction with DNA regulatory elements and indirectly by cross-talk …
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
N Ishihara, M Nomura, A Jofuku, H Kato, SO Suzuki… - Nature cell …, 2009 - nature.com
Mitochondrial morphology is dynamically controlled by a balance between fusion and
fission. The physiological importance of mitochondrial fission in vertebrates is less clearly …
fission. The physiological importance of mitochondrial fission in vertebrates is less clearly …
Nestin-expressing progenitor cells: function, identity and therapeutic implications
The neuroepithelial stem cell protein, or Nestin, is a cytoskeletal intermediate filament
initially characterized in neural stem cells. However, current extensive evidence obtained in …
initially characterized in neural stem cells. However, current extensive evidence obtained in …
Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche
P Codega, V Silva-Vargas, A Paul… - Neuron, 2014 - cell.com
Adult neurogenic niches harbor quiescent neural stem cells; however, their in vivo identity
has been elusive. Here, we prospectively isolate GFAP+ CD133+(quiescent neural stem …
has been elusive. Here, we prospectively isolate GFAP+ CD133+(quiescent neural stem …
[HTML][HTML] Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy
XP ** and adult nervous
systems. These cells are marked by expression of the intermediate filament nestin. We used …
systems. These cells are marked by expression of the intermediate filament nestin. We used …