Mathematical models of the human heart are evolving to become a cornerstone of precision
medicine and support clinical decision making by providing a powerful tool to understand …

Two crucial factors for accurate numerical simulations of cardiac electromechanics, which
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …

We propose a machine learning-based method to build a system of differential equations
that approximates the dynamics of 3D electromechanical models for the human heart …

We developed a novel patient-specific computational model for the numerical simulation of
ventricular electromechanics in patients with ischemic cardiomyopathy (ICM). This model …

Abstract Mechano-electric feedbacks (MEFs), which model how mechanical stimuli are
transduced into electrical signals, have received sparse investigation by considering …

Personalised computer models of cardiac function, referred to as cardiac digital twins, are
envisioned to play an important role in clinical precision therapies of cardiovascular …

Atrial fibrillation (AF) patients are at high risk of stroke, with the left atrial appendage (LAA)
found to be the most common site of clot formation. Presence of left atrial (LA) fibrosis has …

We review and compare different fluid-structure interaction (FSI) numerical methods in the
context of heart modeling, aiming at assessing their computational efficiency for cardiac …

In this work, we address the implementation and performance of inexact Newton–Krylov and
quasi-Newton algorithms, more specifically the BFGS method, for the solution of the …

The results of numerical simulations of cardiac electromechanics are typically characterized
by a long transient before reaching a periodic solution known as limit cycle. This yields a …