Reevaluation of treatment guidelines for Old and New World leishmaniasis is urgently
needed on a global basis because treatment failure is an increasing problem. Drug …

Introduction: Leishmaniasis is a vector-borne neglected tropical disease which manifests as
visceral leishmaniasis (VL), cutaneous leishmaniasis (CL), and mucocutaneous …

It is important to realize that leishmaniasis guidelines cannot always account for individual
variation among patients. They are not intended to supplant physician judgment with respect …

Cutaneous and visceral leishmaniasis are amongst the most devastating infectious diseases
of our time, affecting millions of people worldwide. The treatment of these serious diseases …

Research in visceral leishmaniasis in the last decade has been focused on how better to
use the existing medicines as monotherapy or in combination. Systematic research by …

Introduction: Leishmaniasis broadly manifests as visceral leishmaniasis (VL), cutaneous
leishmaniasis (CL) and mucocutaneous leishmaniasis. The treatment of leishmaniasis is …

Visceral leishmaniasis (VL), caused by the protozoan parasites Leishmania donovani and
Leishmania infantum, is one of the major parasitic diseases worldwide. There is an urgent …

Miltefosine, the only oral drug approved for the treatment of leishmaniasis—a parasitic
disease transmitted by sandflies—is considered as a success story of research and …

Leishmaniasis is a vector-borne disease caused by protozoan parasites of the genus
Leishmania. It is transmitted by phlebotomine female sand flies of the genera Phlebotomus …

For the past 15 years, trials of combination therapy options for visceral leishmaniasis have
been conducted with the aim of identifying effective, and safe treatment regimens that were …