[HTML][HTML] Oxaliplatin and its derivatives–An overview

PD O'Dowd, DF Sutcliffe, DM Griffith - Coordination Chemistry Reviews, 2023 - Elsevier
Oxaliplatin was the third Pt-based anticancer drug to be clinically used worldwide. It exhibits
a broad spectrum of anticancer activity and was the first to be approved for the treatment of …

UiO-66 metal-organic framework nanoparticles as gifted MOFs to the biomedical application: A comprehensive review

M Pourmadadi, MM Eshaghi, S Ostovar… - Journal of Drug Delivery …, 2022 - Elsevier
Metal-organic framework nanoparticles are currently playing an important role in diverse
biomedical applications and it is majorly due to their special structure and combinations of …

Cefazolin encapsulated UIO-66-NH2 nanoparticles enhance the antibacterial activity and biofilm inhibition against drug-resistant S. aureus: In vitro and in vivo studies

A Dastneshan, S Rahiminezhad, MN Meza**… - Chemical Engineering …, 2023 - Elsevier
Antibiotics, which are crucial to treat or prevent bacterial infections, are compounds used to
kill or slow down the growth of bacteria. In recent years, antibiotic resistance has grown into …

Engineered UIO-66 metal-organic framework for delivery of curcumin against breast cancer cells: An in vitro evaluation

S Bazzazan, K Moeinabadi-Bidgoli, ZA Lalami… - Journal of Drug Delivery …, 2023 - Elsevier
Curcumin (Cur) is a traditional herb with known anticancer properties against various
malignancies such as breast cancer. In this study, a metal-organic framework (MOF) based …

UiO-66 nanoparticles as a drug delivery system: A comprehensive review

M Pourmadadi, Z Omrani, Z Forootan, MS Ebadi… - Journal of Drug Delivery …, 2023 - Elsevier
Metal-organic frameworks (MOFs) are coordination polymers that are synthesized by
bonding functional organic ligands with metal ion/cluster nodes.“Cooperation polymers” is a …

A new era in cancer treatment: harnessing ZIF-8 nanoparticles for PD-1 inhibitor delivery

F Rastin, MA Oryani, S Iranpour, H Javid… - Journal of Materials …, 2024 - pubs.rsc.org
This review delves into the potential of zeolitic imidazolate framework-8 (ZIF-8)
nanoparticles in augmenting the efficacy of cancer immunotherapy, with a special focus on …

A pH-responsive bi-MIL-88B MOF coated with folic acid-conjugated chitosan as a promising nanocarrier for targeted drug delivery of 5-Fluorouracil

MU Akbar, S Khattak, MI Khan… - Frontiers in …, 2023 - frontiersin.org
Cancer has remained one of the leading causes of death worldwide, with a lack of effective
treatment. The intrinsic shortcomings of conventional therapeutics regarding tumor …

Magnetic UiO-66-NH2 Core–Shell Nanohybrid as a Promising Carrier for Quercetin Targeted Delivery toward Human Breast Cancer Cells

M Parsaei, K Akhbari - ACS omega, 2023 - ACS Publications
In this study, a magnetic core–shell metal–organic framework (MOF) nanocomposite, Fe3O4-
COOH@ UiO-66-NH2, was synthesized for tumor-targeting drug delivery by incorporating …

Environmentally friendly Zr-based MOF for pesticide delivery: Ultrahigh loading capacity, pH-responsive release, improved leaf affinity, and enhanced antipest activity

S Song, M Wan, W Feng, Y Tian, X Jiang, Y Luo… - Langmuir, 2022 - ACS Publications
The stimuli responsive pesticide delivery system (PDS) has drawn increasing attention in
recent years, a system which can effectively improve the utilization of pesticides. In the …

Carbon monoxide therapy: a promising strategy for cancer

J Chai, J Zhu, Y Tian, K Yang, J Luan… - Journal of Materials …, 2023 - pubs.rsc.org
Cancer is one of the acute life-threatening diseases endangering the whole of humanity.
The treatment modalities for cancer are various. However, in most cases, a single treatment …