Even though stroke presents as a variety of clinical syndromes, neuroimaging is the most
important biomarker to help differentiate between stroke subtypes and assess treatment …

Recent positive trials have thrust acute cerebral perfusion imaging into the routine
evaluation of acute ischemic stroke. Updated guidelines state that in patients with anterior …

The discovery that brain tissue could potentially be salvaged from ischaemia due to stroke,
has led to major advances in the development of therapies for ischemic stroke. In this …

Glutamate plays an important role in excitotoxicity and ferroptosis. Excitotoxicity occurs
through over-stimulation of glutamate receptors, specifically NMDAR, while in the non …

The identification and treatment of patients with stroke is becoming increasingly complex as
more treatment options become available and new relationships between disease features …

Background and Purpose: Different studies have pointed that CT perfusion (CTP) could
overestimate ischemic core in early time window. We aim to evaluate the influence of time …

Stroke is the chief differential diagnosis in patient presenting to the emergency room with
abrupt onset focal neurological deficits. Neuroimaging, including non‐contrast computed …

Background and Objectives To assess the accuracy of baseline CT perfusion (CTP)
ischemic core estimates. Methods From SELECT (Optimizing Patient Selection for …

Objective Mechanical thrombectomy (MT) is not recommended for acute stroke with large
vessel occlusion (LVO) and a large volume of irreversibly injured tissue (“core”). Perfusion …

Despite major advances in prevention, ischaemic stroke remains one of the leading causes
of death and disability worldwide. After centuries of nihilism and decades of failed …