Platinum-based chemotherapy remains the standard-of-care for most patients affected by
advanced non-small cell lung cancer (NSCLC). The platinum compounds currently used in …

Goals of work: Oral and gastrointestinal (GI) mucositis are frequent complications of
chemotherapy and radiotherapy for cancer, contributing to not only the morbidity of treatment …

Background Because the efficacy of carboplatin and cisplatin in the treatment of advanced
non–small-cell lung cancer (NSCLC) has not been proven to be equivalent, an individual …

Objectives Platinum-based chemotherapy is the mainstay of first-line (1L) therapy for
advanced non-small cell cancer (NSCLC). The objective of this study was to evaluate the …

Purpose It remains undetermined whether cisplatin and carboplatin are equally effective for
advanced non–small-cell lung cancer (NSCLC). We therefore did a meta-analysis of trials …

Introduction Mutations in erb-b2 receptor tyrosine kinase 2 (HER2) oncogene are observed
in approximately 3% of lung adenocarcinomas or mixed tumors with adenocarcinoma …

A natural predominant flavonoid hesperidin rich in citrus fruits exhibits multifunctional
medicinal properties. The anticancerous potential of hesperidin has been widely explored; …

Background Lung cancer is the most commonly diagnosed cancer and the leading cause of
cancer death in both sexes worldwide. Approximately 50% of those diagnosed with lung …

OBJECTIVE: Since the debate still exists whether cisplatin-based and carboplatin-based
chemotherapy are equally effective for advanced non-small-cell lung cancer (NSCLC), a …

Purpose This multicenter, open-label, phase I/IIa study was undertaken to establish the
safety/toxicity profile of cetuximab in combination with gemcitabine and carboplatin in …