Nanoprecipitation process: From encapsulation to drug delivery

CJM Rivas, M Tarhini, W Badri, K Miladi… - International journal of …, 2017 - Elsevier
Drugs encapsulation is a suitable strategy in order to cope with the limitations of
conventional dosage forms such as unsuitable bioavailability, stability, taste, and odor …

Polymeric nanoparticles: Promising platform for drug delivery

M Khalid, HS El-Sawy - International journal of pharmaceutics, 2017 - Elsevier
Nano medicine had viewed countless breakthroughs in drug delivery implementations. The
main objective of nanotechnology application in delivering and carrying many promising …

BCS class IV drugs: Highly notorious candidates for formulation development

R Ghadi, N Dand - Journal of Controlled Release, 2017 - Elsevier
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …

Microwave‐assisted synthesis of colloidal inorganic nanocrystals

M Baghbanzadeh, L Carbone… - Angewandte Chemie …, 2011 - Wiley Online Library
Colloidal inorganic nanocrystals stand out as an important class of advanced nanomaterials
owing to the flexibility with which their physical–chemical properties can be controlled …

[HTML][HTML] Application of flash nanoprecipitation to fabricate poorly water-soluble drug nanoparticles

J Tao, SF Chow, Y Zheng - Acta pharmaceutica sinica B, 2019 - Elsevier
Nanoparticles are considered to be a powerful approach for the delivery of poorly water-
soluble drugs. One of the main challenges is develo** an appropriate method for …

Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications

B Fadeel, AE Garcia-Bennett - Advanced drug delivery reviews, 2010 - Elsevier
The development of nanoparticles for biomedical applications including medical imaging
and drug delivery is currently undergoing a dramatic expansion. However, as the range of …

Designs of continuous-flow pharmaceutical crystallizers: developments and practice

M Jiang, RD Braatz - CrystEngComm, 2019 - pubs.rsc.org
Crystallization is an effective, low-cost purification & formulation process widely applied to
pharmaceuticals and fine chemicals. This review describes recent advances in research on …

A simple confined im**ement jets mixer for flash nanoprecipitation

J Han, Z Zhu, H Qian, AR Wohl, CJ Beaman… - Journal of …, 2012 - Elsevier
ABSTRACT Johnson and Prud′ homme (2003. AICHE J 49: 2264–2282) introduced the
confined im**ement jets (CIJ) mixer to prepare nanoparticles loaded with hydrophobic …

Strategies to control the particle size distribution of poly-ε-caprolactone nanoparticles for pharmaceutical applications

F Lince, DL Marchisio, AA Barresi - Journal of colloid and interface science, 2008 - Elsevier
In this work turbulent precipitation through solvent displacement for the production of poly-ε-
caprolactone (PCL) nanoparticles is investigated; two different PCL molecular weights have …

Nanoparticle manufacturing–heterogeneity through processes to products

SM Stavis, JA Fagan, M Stopa… - ACS Applied Nano …, 2018 - ACS Publications
Commercial products are now making use of the unique properties of nanoscale particles.
However, common challenges of making nanoparticles into products still limit their impact. In …