Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

Aims To systematically review the literature on the efficacy and tolerability of the major
chronotherapeutic treatments of bipolar disorders (BD)—bright light therapy (LT), dark …

In the last three decades the two‐process model of sleep regulation has served as a major
conceptual framework in sleep research. It has been applied widely in studies on fatigue …

Mood disorders are often characterised by alterations in circadian rhythms, sleep
disturbances and seasonal exacerbation. Conversely, chronobiological treatments utilise …

Although light therapy (LT) has been shown to be efficient in the treatment of seasonal and
non-seasonal depression, it is underused in clinical settings and antidepressant drugs (AD) …

Depressive syndromes are frequent and heterogeneous brain conditions with more than
90% of patients suffering from sleep complaints. Better characterizing this “sleep” domain …

The circadian system, composed of a network of brain and peripheral 24-hour clocks and
oscillators, allows organisms to anticipate and synchronize to natural daily events. The day …

Study objectives An evening circadian preference is common among adolescents. It is
characterized by a behavioral predilection for later sleep and wake timing and is associated …

The risk of suicide in psychiatric hospitals is 50 times higher than in the general population,
despite patient safety being a priority for any hospital. However, to date, due to the …

Sleep deprivation, alone or in combination with pharmacological treatment and as part of a
chronotherapy package, is of potential use for people with major depressive episodes …