Patient-centred models of hepatitis C treatment for people who inject drugs: a multicentre, pragmatic randomised trial

AH Litwin, PJ Lum, LE Taylor, SH Mehta… - The Lancet …, 2022‏ - thelancet.com
Background To achieve WHO targets for the elimination of hepatitis C virus (HCV) as a
public threat, an increased uptake of HCV treatment among people who inject drugs (PWID) …

[HTML][HTML] Elimination of HCV Infection: Recent Epidemiological Findings, Barriers, and Strategies for the Coming Years

P Torre, M Festa, T Sarcina, M Masarone, M Persico - Viruses, 2024‏ - mdpi.com
Hepatitis C is a disease for which in approximately 30 years we have gone from the
discovery of the causative agent in 1989, to the introduction of direct-acting antiviral (DAAs) …

Declining prevalence of current HCV infection and increased treatment uptake among people who inject drugs: the ETHOS Engage study

H Valerio, M Alavi, A Conway, D Silk, C Treloar… - International Journal of …, 2022‏ - Elsevier
Background Evaluating trends in HCV treatment and prevalence is crucial for monitoring
elimination. We evaluated the change in current infection and treatment among people who …

Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications

F Chalabianloo, LT Fadnes… - Basic & Clinical …, 2024‏ - Wiley Online Library
Background A considerable inter‐individual variability has been reported in the relationship
between methadone doses applied and serum concentrations achieved in methadone …

Peer support in small towns: A decentralized mobile Hepatitis C virus clinic for people who inject drugs

H Midgard, R Bjørnestad, M Egeland, E Dahl… - Liver …, 2022‏ - Wiley Online Library
Abstract Background & Aims New models of HCV care are needed to reach people who
inject drugs (PWID). The primary aim was to evaluate HCV treatment uptake among HCV …

[PDF][PDF] Opportunistic treatment of hepatitis C infection among hospitalized people who inject drugs (OPPORTUNI-C): A stepped wedge cluster randomized trial

H Midgard, KB Malme, CM Pihl… - Clinical Infectious …, 2024‏ - academic.oup.com
Background We aimed to evaluate the efficacy of opportunistic treatment of hepatitis C virus
(HCV) infection among hospitalized people who inject drugs (PWID). Methods We …

Excellent hepatitis C virus cure rates despite increasing complexity of people who use drugs: integrated‐Test‐stage Treat study final outcomes

M O'Sullivan, AM Jones, A Mourad… - Journal of Viral …, 2024‏ - Wiley Online Library
Achieving hepatitic C virus (HCV) elimination requires linking people who use drugs
(PWUD) into care. We report final direct‐acting antivirals (DAAs)‐based outcomes from the …

Monitoring progress towards the elimination of hepatitis C as a public health threat in Norway: a modelling study among people who inject drugs and immigrants

R Whittaker, JE Midtbø… - The Journal of Infectious …, 2024‏ - academic.oup.com
Background The global incidence target for the elimination of hepatitis C among people who
inject drugs (PWID) is< 2/100. In Norway, the hepatitis C epidemic is concentrated in PWID …

[HTML][HTML] Hepatitis C treatment uptake among people who inject drugs in Oslo, Norway: A registry-based study

KB Malme, K Ulstein, AK Finbråten… - International Journal of …, 2023‏ - Elsevier
Background Improving HCV treatment uptake among people who inject drugs (PWID) is
crucial to achieving the WHO elimination targets. The aims were to evaluate HCV treatment …

Virologic response and reinfection following HCV treatment among hospitalized people who inject drugs: follow-up data from the OPPORTUNI-C trial

KB Malme, K Stene-Johansen, I Klundby, Ø Backe… - Viruses, 2024‏ - mdpi.com
Treatment of hepatitis C among people who inject drugs (PWID) may be complicated by loss
to follow-up and reinfection. We aimed to evaluate sustained virologic response (SVR) and …