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Harnessing genomic information for livestock improvement
The world demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has a minimal impact on the environment will …
2050. Meeting this demand in a way that has a minimal impact on the environment will …
1000 bull genomes project to map simple and complex genetic traits in cattle: applications and outcomes
The 1000 Bull Genomes Project is a collection of whole-genome sequences from 2,703
individuals capturing a significant proportion of the world's cattle diversity. So far, 84 million …
individuals capturing a significant proportion of the world's cattle diversity. So far, 84 million …
Ancestry-inclusive dog genomics challenges popular breed stereotypes
Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …
Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology
J Plassais, J Kim, BW Davis, DM Karyadi… - Nature …, 2019 - nature.com
Domestic dog breeds are characterized by an unrivaled diversity of morphologic traits and
breed-associated behaviors resulting from human selective pressures. To identify the …
breed-associated behaviors resulting from human selective pressures. To identify the …
[PDF][PDF] Whole-genome resequencing of worldwide wild and domestic sheep elucidates genetic diversity, introgression, and agronomically important loci
FH Lv, YH Cao, GJ Liu, LY Luo, R Lu… - Molecular biology …, 2022 - academic.oup.com
Domestic sheep and their wild relatives harbor substantial genetic variants that can form the
backbone of molecular breeding, but their genome landscapes remain understudied. Here …
backbone of molecular breeding, but their genome landscapes remain understudied. Here …
A large-scale genome-wide association study in US Holstein cattle
Genome-wide association study (GWAS) is a powerful approach to identify genomic regions
and genetic variants associated with phenotypes. However, only limited mutual confirmation …
and genetic variants associated with phenotypes. However, only limited mutual confirmation …
Conservation, acquisition, and functional impact of sex-biased gene expression in mammals
INTRODUCTION Sex differences are widespread in humans and other mammals. For
example, the distribution of height or body size is shifted upwards in males relative to …
example, the distribution of height or body size is shifted upwards in males relative to …
Meta-analysis of genome-wide association studies provides insights into genetic control of tomato flavor
Tomato flavor has changed over the course of long-term domestication and intensive
breeding. To understand the genetic control of flavor, we report the meta-analysis of genome …
breeding. To understand the genetic control of flavor, we report the meta-analysis of genome …
Functional annotation of animal genomes (FAANG): current achievements and roadmap
Functional annotation of genomes is a prerequisite for contemporary basic and applied
genomic research, yet farmed animal genomics is deficient in such annotation. To address …
genomic research, yet farmed animal genomics is deficient in such annotation. To address …
Genome-wide fine-map** identifies pleiotropic and functional variants that predict many traits across global cattle populations
The difficulty in finding causative mutations has hampered their use in genomic prediction.
Here, we present a methodology to fine-map potentially causal variants genome-wide by …
Here, we present a methodology to fine-map potentially causal variants genome-wide by …