Novel perspective into the interaction behavior study of the cyanidin with human serum albumin-holo transferrin complex: Spectroscopic, calorimetric and molecular …

S Khashkhashi-Moghadam, S Ezazi-Toroghi… - Journal of Molecular …, 2022 - Elsevier
We examined the inducement of an interaction between two carrier proteins, human serum
albumin (HSA) and human holo transferrin (HTF) within the presence of cyanidinin the form …

A comprehensive investigation of interactions between antipsychotic drug quetiapine and human serum albumin using multi-spectroscopic, biochemical, and …

S Zargar, TA Wani, NA Alsaif, AIA Khayyat - Molecules, 2022 - mdpi.com
Quetiapine (QTP) is a short-acting atypical antipsychotic drug that treats schizophrenia or
manic episodes of bipolar disorder. Human serum albumin (HSA) is an essential transport …

Exploring binding interaction of baricitinib with bovine serum albumin (BSA): multi-spectroscopic approaches combined with theoretical calculation

RJ Zhang, SB Kou, L Hu, L Li, JH Shi… - Journal of Molecular …, 2022 - Elsevier
Baricitinib (BRT) is an orally administered small molecule JAK inhibitor, which mainly
inhibits JAK-1 and JAK-2. And it is used to treat autoimmune diseases such as rheumatoid …

Exploring the binding mechanism and adverse toxic effects of persistent organic pollutant (dicofol) to human serum albumin: A biophysical, biochemical and …

S Zargar, TA Wani - Chemico-Biological Interactions, 2021 - Elsevier
The organochlorine pesticide dicofol (DCF), a persistent organic pollutant, is used as
acaricide worldwide. Considering its large consumption in the agriculture sector and …

Mechanistic competitive binding interaction study between olmutinib and colchicine with model transport protein using spectroscopic and computer simulation …

TA Wani, AH Bakheit, S Zargar, S Alamery - Journal of Photochemistry and …, 2022 - Elsevier
Drug-drug interactions are due to the binding of a drug to plasma proteins displacing
another plasma protein-bound drug. Two ligands, olmutinib (OLM) and colchicine (COL) …

Toxicity Study and Binding Analysis of Newly Synthesized Antifungal N-(4-aryl/cyclohexyl)-2-(pyridine-4-yl carbonyl) hydrazinecarbothioamide Derivative with Bovine …

TA Wani, AH Bakheit, S Zargar, N Altwaijry… - International Journal of …, 2023 - mdpi.com
The presence of the p-aryl/cyclohexyl ring in the N-(4-aryl/cyclohexyl)-2-(pyridine-4-yl
carbonyl) hydrazine carbothioamide derivative (2C) is reported to enhance the antifungal …

[HTML][HTML] Influence of rutin, sinapic acid, and naringenin on binding of tyrosine kinase inhibitor erlotinib to bovine serum albumin using analytical techniques along with …

TA Wani, AH Bakheit, S Zargar, AIA Khayyat… - Applied Sciences, 2022 - mdpi.com
Flavonoid-containing food supplements are widely used as antioxidants, and the continuous
use of these supplements with other drugs can lead to clinically significant interactions …

[HTML][HTML] Potential toxic effects of sulfonamides antibiotics: Molecular modeling, multiple-spectroscopy techniques and density functional theory calculations

M Zhu, X Pang, J Wan, X Xu, X Wei, R Hua… - Ecotoxicology and …, 2022 - Elsevier
Sulfonamide antibiotics (SAs) are widely used in medicine, animal husbandry and
aquaculture, and excessive intake of SAs may pose potential toxicity to organisms. The …

[HTML][HTML] Association mechanism and conformational changes in trypsin on its interaction with atrazine: A multi-spectroscopic and biochemical study with computational …

AIA Khayyat, S Zargar, TA Wani, MU Rehman… - International Journal of …, 2022 - mdpi.com
Atrazine (ATR) is a herbicide globally used to eliminate undesired weeds. Herbicide usage
leads to various adverse effects on human health and the environment. The primary source …

Comparison of the interactions of flupyrimin and nitenpyram with serum albumins via multiple analysis methods

Z Zhao, T Shi, Y Chu, Y Cao, S Cheng, R Na, Y Wang - Chemosphere, 2022 - Elsevier
Flupyrimin and nitenpyram are emerging neonicotinoid insecticides that may cause potential
harm to the human body. In the present work, the interactions of flupyrimin/nitenpyram with …