Cognitive impairment is commonly associated with the pain experience. This impairment
represents a major obstacle to daily activities and rehabilitation, especially in the chronic …

A wealth of research over the past 2 decades has expanded our understanding of the impact
of early‐life adversity on physiological function and, consequently, health and wellbeing in …

The purpose of this study was to examine opioid and endocannabinoid mechanisms of
exercise-induced hypoalgesia (EIH). Fifty-eight men and women (mean age= 21 years) …

The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …

The discovery of the endocannabinoid system, comprising the G‐protein coupled
cannabinoid 1 and 2 receptors (CB 1/2), their endogenous lipid ligands or …

Effective therapeutic options for patients living with chronic pain are limited. The pain
relieving effect of cannabinoids remains unclear. A systematic review of randomized …

The therapeutic potential of cannabinoids has been the topic of extensive investigation
following the discovery of cannabinoid receptors and their endogenous ligands …

Endocannabinoids are lipid chemical mediators that act locally by activating cannabinoid
receptors of type 1 (CB 1) and type 2 (CB 2) receptors. The two most-studied …

Cannabis sativa is best known as the source of marijuana, the world's most widely
consumed illicit recreational drug. However, the plant is also extremely useful as a source of …

Research in the cannabinoid field, namely on phytocannabinoids, the endogenous
cannabinoids anandamide and 2-arachidonoyl glycerol and their metabolizing and synthetic …