Copper in tumors and the use of copper-based compounds in cancer treatment

DA da Silva, A De Luca, R Squitti, M Rongioletti… - Journal of inorganic …, 2022 - Elsevier
Copper homeostasis is strictly regulated by protein transporters and chaperones, to allow its
correct distribution and avoid uncontrolled redox reactions. Several studies address copper …

Hydrazone comprising compounds as promising anti-infective agents: Chemistry and structure-property relationship

PC Sharma, D Sharma, A Sharma, N Saini… - Materials Today …, 2020 - Elsevier
Despite the adverse effects of microbial hazards on public health, major pharmaceutical
firms have left the field of anti-infective development and a dramatic reduction in the number …

Correlating the charge transfer efficiency of metallic sulfa-isatins to design efficient NLO materials with better drug designs

S Noreen, SH Sumrra - Biometals, 2022 - Springer
The present study presents synthesis, characterization and first principle studies on metal
chelates,(1–12), of sulfonamide-isatin reacted ligands (S 1–S 3). All the products were …

Aminothiazole-linked metal chelates: synthesis, density functional theory, and antimicrobial studies with antioxidant correlations

S Noreen, SH Sumrra - ACS omega, 2021 - ACS Publications
During the current study, the new aminothiazole Schiff base ligands (S1) and (S2) were
designed by reacting 1, 3-thiazol-2-amine and 6-ethoxy-1, 3-benzothiazole-2-amine …

Metal incorporated sulfonamides as promising multidrug targets: Combined enzyme inhibitory, antimicrobial, antioxidant and theoretical exploration

SH Sumrra, AU Hassan, MN Zafar, SS Shafqat… - Journal of Molecular …, 2022 - Elsevier
In this report, new sulfonamide based ligands (L 1)-(L 3) from 4-amino-N-(pyrimidin-2-yl)
benzene-1-sulfonamide are synthesized and branded on the basis of their physical …

Synthesis, characterization, molecular docking and network pharmacology of bioactive metallic sulfonamide-isatin ligands against promising drug targets

S Noreen, SH Sumrra, ZH Chohan, G Mustafa… - Journal of Molecular …, 2023 - Elsevier
A series of sulfonamide and isatin based Schiff bases,(S 1) and (S 2), and their metal (Co
2+, Ni 2+, Cu 2+ and Zn 2+) complexes (1)-(8) were synthesized and characterized by …

Copper (II) complexes with terpene derivatives of ethylenediamine: synthesis, and antibacterial, antifungal and antioxidant activity

YA Gur'eva, OA Zalevskaya, OG Shevchenko… - RSC …, 2022 - pubs.rsc.org
The synthesis of new chiral copper (II) complexes with terpene derivatives of
ethylenediamine and the results of studying their antibacterial, antifungal and antioxidant …

Dinuclear doubly bridged phenoxido copper (II) complexes as efficient anticancer agents

SS Massoud, FR Louka, NMH Salem… - European Journal of …, 2023 - Elsevier
Abstract Two cationic [Cu 2 (L 1-2) 2](ClO 4) 2 (1, 2), and four neutral doubly bridged-
phenoxido-copper (II) complexes [Cu 2 (L 3-4) 2](3, 4) and [Cu 2 (L 5-6) 2 (H 2 O)]‧ 2H 2 O …

Therapeutic potential of vanadium complexes with 1, 10-phenanthroline ligands, quo vadis? Fate of complexes in cell media and cancer cells

P Nunes, I Correia, I Cavaco, F Marques… - Journal of Inorganic …, 2021 - Elsevier
Abstract V IV O-complexes formulated as [V IV O (OSO 3)(phen) 2](1)(phen= 1, 10-
phenanthroline),[V IV O (OSO 3)(Me 2 phen) 2](2)(Me 2 phen= 4, 7-dimethyl-1, 10 …

Research progress on the biological activities of metal complexes bearing polycyclic aromatic hydrazones

R Liu, J Cui, T Ding, Y Liu, H Liang - Molecules, 2022 - mdpi.com
Due to the abundant and promising biological activities of aromatic hydrazones, it is of great
significance to study the biological activities of their metal complexes for the research and …