Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu… - Chinese chemical …, 2023‏ - Elsevier
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

Ionic liquids: new forms of active pharmaceutical ingredients with unique, tunable properties

JL Shamshina, RD Rogers - Chemical Reviews, 2023‏ - ACS Publications
This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …

Nanoparticle protein corona: from structure and function to therapeutic targeting

G Bashiri, MS Padilla, KL Swingle, SJ Shepherd… - Lab on a Chip, 2023‏ - pubs.rsc.org
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …

Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases

G Li, T Chen, J Dahlman… - Journal of …, 2023‏ - Wiley Online Library
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids,
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …

A perspective on polylactic acid-based polymers use for nanoparticles synthesis and applications

T Casalini, F Rossi, A Castrovinci… - … in bioengineering and …, 2019‏ - frontiersin.org
Polylactic acid (PLA)—based polymers are ubiquitous in the biomedical field thanks to their
combination of attractive peculiarities: biocompatibility (degradation products do not elicit …

Stealth coating of nanoparticles in drug-delivery systems

SY Fam, CF Chee, CY Yong, KL Ho… - Nanomaterials, 2020‏ - mdpi.com
Nanoparticles (NPs) have emerged as a powerful drug-delivery tool for cancer therapies to
enhance the specificity of drug actions, while reducing the systemic side effects …

Progress, challenges, and future of nanomedicine

C Zhang, L Yan, X Wang, S Zhu, C Chen, Z Gu, Y Zhao - Nano Today, 2020‏ - Elsevier
Nanotherapeutics exhibit unique advantages in clinical outcomes compared with
conventional small molecular drugs. The past three decades have seen intensive research …

Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities

F Farjadian, A Ghasemi, O Gohari, A Roointan… - …, 2019‏ - Taylor & Francis
There has been a revolution in nanotechnology and nanomedicine. Since 1980, there has
been a remarkable increase in approved nano-based pharmaceutical products. These novel …

M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma

X Zuo, Z Chen, W Gao, Y Zhang, J Wang… - Journal of hematology & …, 2020‏ - Springer
Abstract Background Long non-coding RNAs (lncRNAs) possess significant regulatory
functions in multiple biological and pathological processes, especially in cancer …

Nanoparticles of metal‐organic frameworks: on the road to in vivo efficacy in biomedicine

T Simon‐Yarza, A Mielcarek, P Couvreur… - Advanced …, 2018‏ - Wiley Online Library
In the past few years, numerous studies have demonstrated the great potential of nano
particles of metal‐organic frameworks (nanoMOFs) at the preclinical level for biomedical …