Neuromodulation by the immune system: a focus on cytokines

AF Salvador, KA de Lima, J Kipnis - Nature Reviews Immunology, 2021 - nature.com
Interactions between the immune system and the nervous system have been described
mostly in the context of diseases. More recent studies have begun to reveal how certain …

Why is everyone talking about brain state?

AS Greene, C Horien, D Barson, D Scheinost… - Trends in …, 2023 - cell.com
The rapid and coordinated propagation of neural activity across the brain provides the
foundation for complex behavior and cognition. Technical advances across neuroscience …

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems

KY Chan, MJ Jang, BB Yoo, A Greenbaum, N Ravi… - Nature …, 2017 - nature.com
Adeno-associated viruses (AAVs) are commonly used for in vivo gene transfer.
Nevertheless, AAVs that provide efficient transduction across specific organs or cell …

Distributed coding of choice, action and engagement across the mouse brain

NA Steinmetz, P Zatka-Haas, M Carandini, KD Harris - Nature, 2019 - nature.com
Vision, choice, action and behavioural engagement arise from neuronal activity that may be
distributed across brain regions. Here we delineate the spatial distribution of neurons …

Single-trial neural dynamics are dominated by richly varied movements

S Musall, MT Kaufman, AL Juavinett, S Gluf… - Nature …, 2019 - nature.com
When experts are immersed in a task, do their brains prioritize task-related activity? Most
efforts to understand neural activity during well-learned tasks focus on cognitive …

Deep posteromedial cortical rhythm in dissociation

S Vesuna, IV Kauvar, E Richman, F Gore, T Oskotsky… - Nature, 2020 - nature.com
Advanced imaging methods now allow cell-type-specific recording of neural activity across
the mammalian brain, potentially enabling the exploration of how brain-wide dynamical …

The emergence and influence of internal states

SW Flavell, N Gogolla, M Lovett-Barron, M Zelikowsky - Neuron, 2022 - cell.com
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

Genetic dissection of neural circuits: a decade of progress

L Luo, EM Callaway, K Svoboda - Neuron, 2018 - cell.com
Tremendous progress has been made since Neuron published our Primer on genetic
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …

Gene therapy for neurological disorders: progress and prospects

BE Deverman, BM Ravina, KS Bankiewicz… - Nature Reviews Drug …, 2018 - nature.com
Adeno-associated viral (AAV) vectors are a rapidly emerging gene therapy platform for the
treatment of neurological diseases. In preclinical studies, transgenes encoding therapeutic …

Thirst regulates motivated behavior through modulation of brainwide neural population dynamics

WE Allen, MZ Chen, N Pichamoorthy, RH Tien… - Science, 2019 - science.org
INTRODUCTION Motivational drives are internal states that can explain why animals
adaptively display distinct behaviors in response to the same external stimulus …