Significant advancements have been made in recent years in the development of highly
sophisticated skin organoids. Serving as three-dimensional models that mimic human skin …

Much effort has been made to generate human skin organ in the laboratory. Yet, the current
models are limited due to the lack of many critical biological and structural features of the …

This review on acne transcriptomics allows for deeper insights into the pathogenesis of acne
and isotretinoin's mode of action. Puberty-induced insulin-like growth factor 1 (IGF-1), insulin …

Organoids are 3D models of organs, grown in the laboratory from stem cells. An organ
model grown/placed in microfluidic devices is commonly termed an “organ-on-a-chip” …

Sebaceous glands (SGs) release oils that protect our skin, but how these glands respond to
injury has not been previously examined. Here, we report that SGs are largely self-renewed …

Skin aging is influenced by intrinsic and extrinsic factors that progressively impair skin
functionality over time. Investigating the skin aging process requires thorough research …

Sebaceous glands (SGs) originate from hair follicular stem cells and secrete lipids to
lubricate the skin. The coordinated effects of intrinsic and extrinsic aging factors generate …

Organoid technologies represent a major breakthrough in biomedical research since they
offer increasingly sophisticated models for studying biological mechanisms supporting …

Sebaceous glands (SGs), typically associated with hair follicles, are critical for the
homeostasis and function of mammalian skin. The main physiological function of SGs is the …

As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenoty** of patient-
derived organoids is desirable to identify drug-induced changes and trace metabolic …