Ultrafast excited-state dynamics in nucleic acids
The scope of this review is the nature and dynamics of the singlet excited electronic states
created in nucleic acids and their constituents by UV light. Interest in the UV photochemistry …
created in nucleic acids and their constituents by UV light. Interest in the UV photochemistry …
Dynamics of water in biological recognition
SK Pal, AH Zewail - Chemical Reviews, 2004 - ACS Publications
Almost all biological macromoleculessproteins (enzymes) and DNAsare inactive in the
absence of water. Hydration of a protein/enzyme is particularly important for the stability of …
absence of water. Hydration of a protein/enzyme is particularly important for the stability of …
Singlet excited-state behavior of uracil and thymine in aqueous solution: a combined experimental and computational study of 11 uracil derivatives
T Gustavsson, A Bányász, E Lazzarotto… - Journal of the …, 2006 - ACS Publications
The excited-state properties of uracil, thymine, and nine other derivatives of uracil have been
studied by steady-state and time-resolved spectroscopy. The excited-state lifetimes were …
studied by steady-state and time-resolved spectroscopy. The excited-state lifetimes were …
Internal conversion to the electronic ground state occurs via two distinct pathways for pyrimidine bases in aqueous solution
The femtosecond transient absorption technique was used to study the relaxation of excited
electronic states created by absorption of 267-nm light in all of the naturally occurring …
electronic states created by absorption of 267-nm light in all of the naturally occurring …
Adenine and 2-aminopurine: paradigms of modern theoretical photochemistry
L Serrano-Andres, M Merchan… - Proceedings of the …, 2006 - National Acad Sciences
Distinct photophysical behavior of nucleobase adenine and its constitutional isomer, 2-
aminopurine, has been studied by using quantum chemical methods, in particular an …
aminopurine, has been studied by using quantum chemical methods, in particular an …
Water at DNA surfaces: ultrafast dynamics in minor groove recognition
SK Pal, L Zhao, AH Zewail - Proceedings of the National …, 2003 - National Acad Sciences
Water molecules at the surface of DNA are critical to its equilibrium structure, DNA–protein
function, and DNA–ligand recognition. Here we report direct probing of the dynamics of …
function, and DNA–ligand recognition. Here we report direct probing of the dynamics of …
An efficient statistically converged average configuration for solvent effects
Using statistically uncorrelated solute–solvent configurations generated by Monte Carlo
simulation a simpler and efficient implementation of the averaged solvent electrostatic …
simulation a simpler and efficient implementation of the averaged solvent electrostatic …
Femtosecond broadband fluorescence upconversion spectroscopy: Improved setup and photometric correction
A setup for fluorescence upconversion spectroscopy (FLUPS) is described which has 80 fs
temporal response (fwhm) for emission in the spectral range 425–750 nm. Broadband …
temporal response (fwhm) for emission in the spectral range 425–750 nm. Broadband …
Ultrafast surface hydration dynamics and expression of protein functionality: α-Chymotrypsin
We report studies of hydration dynamics at the surface of the enzyme protein bovine
pancreatic α-chymotrypsin. The probe is the well known 1-anilinonaphthalene-8-sulfonate …
pancreatic α-chymotrypsin. The probe is the well known 1-anilinonaphthalene-8-sulfonate …
Switching on the fluorescence of 2-aminopurine by site-selective microhydration
Aminopurine (2AP) is a fluorescent isomer of adenine and has a fluorescence lifetime of~ 11
ns in water. It is widely used in biochemical settings as a site-specific fluorescent probe of …
ns in water. It is widely used in biochemical settings as a site-specific fluorescent probe of …