This review summarises the evidence that chronic low grade inflammation triggers changes
that contribute to the mental and physical ill health of patients with major depression …

The current paper reviews research that has explored the intergenerational effects of the
Indian Residential School (IRS) system in Canada, in which Aboriginal children were forced …

Siloed or singular system approach to disease management is common practice,
develo** out of traditional medical school education. Textbooks of medicine describe a …

A growing body of research shows that social networks and identities have a profound
impact on mental and physical health. With such mounting evidence of the importance of …

Background In recent years, proinflammatory cytokine interleukin-1β (IL-1β) was considered
to play a critical role in the pathogenesis of depression. In addition, P2X7 receptor (P2X7R) …

The potential contribution of chronic inflammation to the development of neuropsychiatric
disorders such as major depression has received increasing attention. Elevated biomarkers …

Anhedonia is a core symptom of major depressive disorder (MDD), the neurobiological
mechanisms of which remain poorly understood. Despite decades of speculation regarding …

Recognition that inflammation may represent a common mechanism of disease has been
extended to include neuropsychiatric disorders including major depression. Patients with …

Psychiatric disorders are associated with serve disturbances in cognition, emotional control,
or behavior regulation, yet few routine clinical tools are available for the real-time evaluation …

Increasing evidence indicates that chronic obstructive pulmonary disease (COPD) is a
complex disease involving more than airflow obstruction. Airflow obstruction has profound …