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The tumor microenvironment: a milieu hindering and obstructing antitumor immune responses
A Labani-Motlagh, M Ashja-Mahdavi… - Frontiers in …, 2020 - frontiersin.org
The success of cancer immunotherapy relies on the knowledge of the tumor
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …
Exosome-based immunotherapy: a promising approach for cancer treatment
Z Xu, S Zeng, Z Gong, Y Yan - Molecular cancer, 2020 - Springer
In the era of the rapid development of cancer immunotherapy, there is a high level of interest
in the application of cell-released small vesicles that stimulate the immune system. As cell …
in the application of cell-released small vesicles that stimulate the immune system. As cell …
Engineered extracellular vesicles and their mimetics for cancer immunotherapy
C Liu, Y Wang, L Li, D He, J Chi, Q Li, Y Wu… - Journal of Controlled …, 2022 - Elsevier
Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by living
cells that are involved in many physiological and pathological processes as intermediaries …
cells that are involved in many physiological and pathological processes as intermediaries …
Extracellular‐vesicle‐based drug delivery systems for enhanced antitumor therapies through modulating the cancer‐immunity cycle
T Yong, Z Wei, L Gan, X Yang - Advanced Materials, 2022 - Wiley Online Library
Although immunotherapy harnessing activity of the immune system against tumors has
made great progress, the treatment efficacy remains limited in most cancers. Current …
made great progress, the treatment efficacy remains limited in most cancers. Current …
[HTML][HTML] Exosome regulation of immune response mechanism: Pros and cons in immunotherapy
Due to its multiple features, including the ability to orchestrate remote communication
between different tissues, the exosomes are the extracellular vesicles arousing the highest …
between different tissues, the exosomes are the extracellular vesicles arousing the highest …
Modification of immune cell-derived exosomes for enhanced cancer immunotherapy: current advances and therapeutic applications
Cancer immunotherapy has revolutionized the approach to cancer treatment of malignant
tumors by harnessing the body's immune system to selectively target cancer cells. Despite …
tumors by harnessing the body's immune system to selectively target cancer cells. Despite …
The exosomes derived from CAR-T cell efficiently target mesothelin and reduce triple-negative breast cancer growth
P Yang, X Cao, H Cai, P Feng, X Chen, Y Zhu… - Cellular …, 2021 - Elsevier
Genetically engineered T cells expressing a chimeric antigen receptor (CAR) have rapidly
developed into a powerful and innovative therapeutic modality for cancer patients. However …
developed into a powerful and innovative therapeutic modality for cancer patients. However …
Extracellular vesicles as next generation immunotherapeutics
Extracellular vesicles (EVs) function as a mode of intercellular communication and
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …
Immune cell-derived extracellular vesicles–new strategies in cancer immunotherapy
P Yang, Y Peng, Y Feng, Z Xu, P Feng, J Cao… - Frontiers in …, 2021 - frontiersin.org
Immune cell-derived extracellular vesicles (EVs) have increasingly become the focus of
research due to their unique characteristics and bioinspired applications. They are lipid …
research due to their unique characteristics and bioinspired applications. They are lipid …
The roles of small extracellular vesicles in cancer and immune regulation and translational potential in cancer therapy
Extracellular vesicles (EVs) facilitate the extracellular transfer of proteins, lipids, and nucleic
acids and mediate intercellular communication among multiple cells in the tumour …
acids and mediate intercellular communication among multiple cells in the tumour …