A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

[HTML][HTML] Circulating tumor cell technologies

MM Ferreira, VC Ramani, SS Jeffrey - Molecular oncology, 2016 - Elsevier
Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of …

Androgen receptor splice variant 7 and efficacy of taxane chemotherapy in patients with metastatic castration-resistant prostate cancer

ES Antonarakis, C Lu, B Luber, H Wang, Y Chen… - JAMA …, 2015 - jamanetwork.com
Importance We previously showed that detection of androgen receptor splice variant 7 (AR-
V7) in circulating tumor cells (CTCs) from men with castration-resistant prostate cancer …

Blood-based analyses of cancer: circulating tumor cells and circulating tumor DNA

DA Haber, VE Velculescu - Cancer discovery, 2014 - AACR
The ability to study nonhematologic cancers through noninvasive sampling of blood is one
of the most exciting and rapidly advancing fields in cancer diagnostics. This has been driven …

Circulating tumor cells and circulating tumor DNA: challenges and opportunities on the path to clinical utility

M Ignatiadis, M Lee, SS Jeffrey - Clinical Cancer Research, 2015 - AACR
Recent technological advances have enabled the detection and detailed characterization of
circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) in blood samples from …

The growing role of precision and personalized medicine for cancer treatment

P Krzyszczyk, A Acevedo, EJ Davidoff, LM Timmins… - Technology, 2018 - World Scientific
Cancer is a devastating disease that takes the lives of hundreds of thousands of people
every year. Due to disease heterogeneity, standard treatments, such as chemotherapy or …

Advancing the speed, sensitivity and accuracy of biomolecular detection using multi-length-scale engineering

SO Kelley, CA Mirkin, DR Walt, RF Ismagilov… - Nature …, 2014 - nature.com
Rapid progress in identifying disease biomarkers has increased the importance of creating
high-performance detection technologies. Over the last decade, the design of many …

Organ-on-a-chip platforms for studying drug delivery systems

NS Bhise, J Ribas, V Manoharan, YS Zhang… - Journal of Controlled …, 2014 - Elsevier
Novel microfluidic tools allow new ways to manufacture and test drug delivery systems.
Organ-on-a-chip systems—microscale recapitulations of complex organ functions—promise …

Circulating tumor cells: clinical validity and utility

L Cabel, C Proudhon, H Gortais, D Loirat… - International journal of …, 2017 - Springer
Circulating tumor cells (CTCs) are rare tumor cells and have been investigated as
diagnostic, prognostic and predictive biomarkers in many types of cancer. Although CTCs …

[HTML][HTML] Detecting circulating tumor cells: current challenges and new trends

B Hong, Y Zu - Theranostics, 2013 - ncbi.nlm.nih.gov
Circulating tumor cells (CTCs) in the blood stream play a critical role in establishing
metastases. The clinical value of CTCs as a biomarker for early cancer detection, diagnosis …