Next-generation, personalised, model-based critical care medicine: a state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to …
Critical care, like many healthcare areas, is under a dual assault from significantly
increasing demographic and economic pressures. Intensive care unit (ICU) patients are …
increasing demographic and economic pressures. Intensive care unit (ICU) patients are …
Optimising mechanical ventilation through model-based methods and automation
Mechanical ventilation (MV) is a core life-support therapy for patients suffering from
respiratory failure or acute respiratory distress syndrome (ARDS). Respiratory failure is a …
respiratory failure or acute respiratory distress syndrome (ARDS). Respiratory failure is a …
Network data acquisition and monitoring system for intensive care mechanical ventilation treatment
The rise of model-based and machine learning methods have created increasingly realistic
opportunities to implement personalized, patient-specific mechanical ventilation (MV) in the …
opportunities to implement personalized, patient-specific mechanical ventilation (MV) in the …
Prediction and estimation of pulmonary response and elastance evolution for volume-controlled and pressure-controlled ventilation
Mechanical ventilation (MV) is a core treatment for patients suffering from respiratory
disease and failure. However, MV settings are not standardized due to significant inter-and …
disease and failure. However, MV settings are not standardized due to significant inter-and …
A virtual patient model for mechanical ventilation
Abstract Background and Objectives Mechanical ventilation (MV) is a primary therapy for
patients with acute respiratory failure. However, poorly selected ventilator settings can cause …
patients with acute respiratory failure. However, poorly selected ventilator settings can cause …
Model-based PEEP titration versus standard practice in mechanical ventilation: a randomised controlled trial
Background Positive end-expiratory pressure (PEEP) at minimum respiratory elastance
during mechanical ventilation (MV) in patients with acute respiratory distress syndrome …
during mechanical ventilation (MV) in patients with acute respiratory distress syndrome …
Assessing mechanical ventilation asynchrony through iterative airway pressure reconstruction
Background and objective Respiratory mechanics estimation can be used to guide
mechanical ventilation (MV) but is severely compromised when asynchronous breathing …
mechanical ventilation (MV) but is severely compromised when asynchronous breathing …
Evaluation of model-based methods in estimating respiratory mechanics in the presence of variable patient effort
Monitoring of respiratory mechanics is required for guiding patient-specific mechanical
ventilation settings in critical care. Many models of respiratory mechanics perform poorly in …
ventilation settings in critical care. Many models of respiratory mechanics perform poorly in …
Clinical application of respiratory elastance (CARE trial) for mechanically ventilated respiratory failure patients: a model-based study
Mechanical ventilation (MV) is the primary support for respiratory failure patients. MV
treatment is difficult to manage due to the variable patient-specific disease state and …
treatment is difficult to manage due to the variable patient-specific disease state and …
Quantifying neonatal pulmonary mechanics in mechanical ventilation
Abstract Background Mechanical Ventilation (MV) is an important intensive care therapy. It is
often used in neonatal intensive care units (NICUs) to treat respiratory distress syndrome …
often used in neonatal intensive care units (NICUs) to treat respiratory distress syndrome …