[HTML][HTML] The neurochemistry of autism

R Marotta, MC Risoleo, G Messina, L Parisi… - Brain sciences, 2020 - mdpi.com
Autism spectrum disorder (ASD) refers to complex neurobehavioral and
neurodevelopmental conditions characterized by impaired social interaction and …

[HTML][HTML] Is melatonin the cornucopia of the 21st century?

N Ferlazzo, G Andolina, A Cannata, MG Costanzo… - Antioxidants, 2020 - mdpi.com
Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …

Risk and protective environmental factors associated with autism spectrum disorder: evidence-based principles and recommendations

L Emberti Gialloreti, L Mazzone, A Benvenuto… - Journal of clinical …, 2019 - mdpi.com
Autism Spectrum Disorder (ASD) is a complex condition with early childhood onset,
characterized by a set of common behavioral features. The etiology of ASD is not yet fully …

Sleep problems in children with autism spectrum disorder: a multicenter survey

H Chen, T Yang, J Chen, L Chen, Y Dai, J Zhang, L Li… - BMC psychiatry, 2021 - Springer
Background High prevalence of sleep problems have been reported in children with Autism
Spectrum Disorder (ASD). This study aims to investigate the sleep conditions of ASD …

Melatonin for sleep disorders in people with autism: Systematic review and meta-analysis

HA Nogueira, CT de Castro, DCG da Silva… - Progress in neuro …, 2023 - Elsevier
Melatonin is a potential therapeutic intervention for improving sleep quality in people with
autistic spectrum disorder (ASD). We investigate the effect of using melatonin as a sleep …

Melatonin: from pharmacokinetics to clinical use in autism spectrum disorder

S Lalanne, C Fougerou-Leurent, GM Anderson… - International Journal of …, 2021 - mdpi.com
The role of melatonin has been extensively investigated in pathophysiological conditions,
including autism spectrum disorder (ASD). Reduced melatonin secretion has been reported …

Nutritional modulation of the intestinal microbiota; future opportunities for the prevention and treatment of neuroimmune and neuroinflammatory disease

VC Lombardi, KL De Meirleir, K Subramanian… - The Journal of nutritional …, 2018 - Elsevier
The gut–brain axis refers to the bidirectional communication between the enteric nervous
system and the central nervous system. Mounting evidence supports the premise that the …

[HTML][HTML] Efficacy and safety of melatonin treatment in children with Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder—a review of the literature

B Rzepka-Migut, J Paprocka - Brain sciences, 2020 - mdpi.com
Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are
neurodevelopmental disorders with disturbed melatonin secretion profile and sleep …

[HTML][HTML] Autism spectrum disorder (ASD): disturbance of the melatonin system and its implications

Z Wu, J Zou, Q Wang, M Naveed, H Bao… - biomedicine & …, 2020 - Elsevier
The molecular mechanisms underlying autism spectrum disorder (ASD) remain elusive,
which limits the management options available in the clinic. Accumulating evidence …

The trilateral interactions between mammalian target of rapamycin (mTOR) signaling, the circadian clock, and psychiatric disorders: an emerging model

R Singla, A Mishra, R Cao - Translational psychiatry, 2022 - nature.com
Abstract Circadian (~ 24 h) rhythms in physiology and behavior are evolutionarily conserved
and found in almost all living organisms. The rhythms are endogenously driven by daily …