Ageing and chronic degenerative pathologies demonstrate the shared characteristics of
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …

Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …

As an important application of functional biomaterials, neural probes have contributed
substantially to studying the brain. Bioinspired and biomimetic strategies have begun to be …

Depression is a polygenic and highly complex psychiatric disorder that remains a major
burden on society. Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) …

Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the
most attention, because it is involved in higher cognitive function, most notably memory …

Neurodegenerative diseases are disabling and fatal neurological disorders that currently
lack effective treatment. Neural stem cell (NSC) transplantation has been studied as a …

Cytokines are pleiotropic molecules with important roles in inflammatory responses. Pro-
inflammatory cytokines and neuroinflammation are important not only in inflammatory …

Specialized adult somatic cells, such as cardiomyocytes (CMs), are highly differentiated with
poor renewal capacity, an integral reason underlying organ failure in disease and aging …

Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate …

Throughout life, new neurons are continuously added to the dentate gyrus. As this
continuous addition remodels hippocampal circuits, computational models predict that …