Generation of reactive oxygen species and related oxidants is an inevitable consequence of
life. Proteins are major targets for oxidation reactions, because of their rapid reaction rates …

Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease that inevitably
progress to end-stage kidney disease. Intervention strategies such as blood glucose control …

Abstract Purpose of Review Diabetes mellitus is a complex, chronic illness characterized by
elevated blood glucose levels that occurs when there is cellular resistance to insulin action …

The formation of advanced glycation end products (AGEs) in foods is accelerated with heat
treatment, particularly within foods that are cooked at high temperatures for long periods of …

Proteinopathy and excessive production of reactive oxygen species (ROS), which are the
principal features observed in the Alzheimer's disease (AD) brain, contribute to neuronal …

Breakthroughs in biochemistry have furthered our understanding of the onset and
progression of various diseases, and have advanced the development of new therapeutics …

Diets are currently characterized by elevated sugar intake, mainly due to the increased
consumption of processed sweetened foods and drinks during the last 40 years. Diet is the …

Risk of cancer especially of colon, breast, and pancreas is high in diabetic and obese
patients, with potential involvement of augmented expression of RAGE (receptor for …

Advanced glycation end products (AGEs), a heterogeneous group of compounds formed by
nonenzymatic glycation reactions between reducing sugars and amino acids, lipids, or DNA …

Contemporary medicine is shifting towards person rather than disease-oriented care. 1 With
increasing life expectancy and the ageing of baby boomers, the proportion over 60 years is …