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Real-Time Monitoring of Oxygen-Consumption Rate in Mouse Liver Slices Incubated in Organ-on-a-Chip Devices
REH Karsten, K Gier, JPSH Mulder… - Analytical …, 2024 - ACS Publications
We developed an organ-on-a-chip (OOC) based on precision-cut liver slices to assess liver
function in real-time, both in health and disease, in a controlled and noninvasive manner …
function in real-time, both in health and disease, in a controlled and noninvasive manner …
The liver's (mal) functions magnified
R Karsten - 2024 - research.rug.nl
Drug-induced cholestasis (DIC) is the impairment of intra-and extra-hepatic bile flow caused
by drugs. When chronic, DIC can lead to fibrosis, cirrhosis, and eventually organ failure …
by drugs. When chronic, DIC can lead to fibrosis, cirrhosis, and eventually organ failure …