Harnessing the Potential of Real-World Evidence in the Treatment of Colorectal Cancer: Where Do We Stand?

SCMW van Nassau, GM Bol, FH van der Baan… - … treatment options in …, 2024 - Springer
Opinion statement Treatment guidelines for colorectal cancer (CRC) are primarily based on
the results of randomized clinical trials (RCTs), the gold standard methodology to evaluate …

Five-year follow-up mortality prognostic index for colorectal patients

M Orive, I Barrio, S Lázaro, N Gonzalez, M Bare… - International journal of …, 2023 - Springer
Purpose To identify 5-year survival prognostic variables in patients with colorectal cancer
(CRC) and to propose a survival prognostic score that also takes into account changes over …

Estimating postoperative mortality in colorectal surgery-a systematic review of risk prediction models

A Dosis, J Helliwell, A Syversen, J Tiernan… - International Journal of …, 2023 - Springer
Purpose Risk prediction models are frequently used to support decision-making in colorectal
surgery but can be inaccurate. Machine learning (ML) is becoming increasingly popular, and …

Low muscle mass is associated with a higher risk of all–cause and cardiovascular disease–specific mortality in cancer survivors

D Zhang, KA Spiropoulos, A Wijayabahu, DD Christou… - Nutrition, 2023 - Elsevier
Objectives Individuals with prior cancer diagnosis are more likely to have low muscle mass
(LMM) than their cancer-free counterparts. Understanding the effects of LMM on the …

[HTML][HTML] Failure to rescue after reoperation for major complications of elective and emergency colorectal surgery: a population-based multicenter cohort study

MT Grönroos-Korhonen, LE Koskenvuo, PJ Mentula… - Surgery, 2022 - Elsevier
Background As surgical complications inevitably occur, minimizing the failure-to-rescue rate
is of paramount interest. Most of the failure-to-rescue research in colorectal surgery has …

Introducing machine learning-based prediction models in the perioperative setting

I Gögenur - British Journal of Surgery, 2023 - academic.oup.com
Facing the challenge of every second patient develo** complications arising from surgery
1, it is intriguing that the next major advancements in perioperative care will be technological …

Risk of Mortality Following Surgery in Patients With a Previous Cardiovascular Event

CV Chalitsios, MS Luney, WA Lindsay… - JAMA …, 2024 - jamanetwork.com
Importance There is a lack of consensus regarding the interval of time-dependent
postoperative mortality risk following acute coronary syndrome or stroke. Objective To …

Understanding outcomes after major surgery

DA Harvie, DZH Levett, MPW Grocott - Anesthesia & Analgesia, 2023 - journals.lww.com
The global volume of surgery is increasing. Adverse outcomes after surgery have resource
implications and long-term impact on quality of life and consequently represent a significant …

The pulmonary surgical Apgar score for lung cancer surgery predicts postoperative complications and long-term survival

H Hino, S Hagihira, N Maru, T Utsumi… - European Journal of …, 2023 - academic.oup.com
OBJECTIVES The surgical Apgar score, calculated using 3 intraoperative variables (blood
loss, lowest mean arterial pressure and lowest heart rate), is associated with mortality in …

Develo** prediction models for short-term mortality after surgery for colorectal cancer using a Danish national quality assurance database

KB Bräuner, AW Rosen, A Tsouchnika… - International Journal of …, 2022 - Springer
Purpose The majority of colorectal cancer surgeries are performed electively, and treatment
is often decided at the multidisciplinary team conference. Although the average 30-day …