Rheumatoid arthritis (RA) is an inflammatory disease typically affecting the joints, but the
systemic inflammatory process may involve other tissues and organs. Many extra-articular …

Autoimmune diseases are considered as one of the most important disorders of the immune
system, in which the prolonged and chronic processes eliminate self-tolerance to the auto …

Cytokine storm induced by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by articular and
systemic manifestations, such as anemia, fatigue, osteoporosis, and increased risk for …

Sjögren's syndrome (SS) is a chronic autoimmune disease that primarily affects the exocrine
glands, resulting in their functional impairment. In SS, lymphocytic infiltration of salivary and …

Macrophages are pivotal cells involved in chronic inflammatory and autoimmune diseases.
In fact, during these diseases, activated macrophages may play a critical role, promoting the …

The five TNF inhibitors currently approved for the treatment of RA are characterised by
differences in their molecular structures, half-lives, administration routes, dosing intervals …

Autoimmune rheumatic diseases are characterised by an abnormal immune system
response, complement activation, cytokines dysregulation and inflammation. In last years …

M281 is a fully human, anti‐neonatal Fc receptor (FcRn) antibody that inhibits FcRn‐
mediated immunoglobulin G (IgG) recycling to decrease pathogenic IgG while preserving …

Inflammatory rheumatic diseases are different pathologic conditions associated with a
deregulated immune response, codified along a spectrum of disorders, with …