Objective: The authors provide an evidenced-based summary of the literature on the clinical
application of psychedelic drugs in psychiatric disorders. Methods: Searches of PubMed and …

This paper introduces a new construct, the 'pivotal mental state', which is defined as a hyper-
plastic state aiding rapid and deep learning that can mediate psychological transformation …

Addressing global mental health is a major 21st-century challenge. Current treatments have
recognized limitations; in this context, new ones that are prophylactic and effective across …

Research on psychedelics has seen a recent revival, with many clinical trials focused on
their therapeutic potential to treat a range of mental health conditions. The purpose of this …

In the last 15 years, psychedelic substances, such as LSD and psilocybin, have regained
legitimacy in clinical research. In the general population as well as across various …

Provides a timely update to a key textbook on human drug metabolism The third edition of
this comprehensive book covers basic concepts of teaching drug metabolism, starting from …

The use of psychedelics for various purposes was common in different civilizations
throughout human history and has been explored scientifically for more than a century …

BackgroundScientific interest in the therapeutic effects of classical psychedelics has
increased in the past two decades. The psychological effects of these substances outside …

Research over the past several decades suggests that meaningful psychedelic experiences
can engender long-term effects on subjective wellbeing. However, less research has …

Serotonergic psychedelics such as psilocybin, lysergic acid diethylamide (LSD), or
dimethyltryptamine (DMT), as well as psychoactive drugs that trigger phenomenologically …