Mass spectrometry-based metabolomics in microbiome investigations
Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …
Microbiota succession throughout life from the cradle to the grave
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …
microbial composition at several body sites can predict human chronological age relatively …
Multi-level analysis of the gut–brain axis shows autism spectrum disorder-associated molecular and microbial profiles
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …
Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma
The composition of the gut microbiome has been associated with clinical responses to
immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific …
immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific …
Microbiome differential abundance methods produce different results across 38 datasets
Identifying differentially abundant microbes is a common goal of microbiome studies.
Multiple methods are used interchangeably for this purpose in the literature. Yet, there are …
Multiple methods are used interchangeably for this purpose in the literature. Yet, there are …
Climate warming enhances microbial network complexity and stability
Unravelling the relationships between network complexity and stability under changing
climate is a challenging topic in theoretical ecology that remains understudied in the field of …
climate is a challenging topic in theoretical ecology that remains understudied in the field of …
Estimated transmissibility and impact of SARS-CoV-2 lineage B. 1.1. 7 in England
INTRODUCTION Several novel variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the virus that causes COVID-19, emerged in late 2020. One of these, Variant …
(SARS-CoV-2), the virus that causes COVID-19, emerged in late 2020. One of these, Variant …
Analysis of compositions of microbiomes with bias correction
H Lin, SD Peddada - Nature communications, 2020 - nature.com
Differential abundance (DA) analysis of microbiome data continues to be a challenging
problem due to the complexity of the data. In this article we define the notion of “sampling …
problem due to the complexity of the data. In this article we define the notion of “sampling …
Multigroup analysis of compositions of microbiomes with covariate adjustments and repeated measures
H Lin, SD Peddada - Nature Methods, 2024 - nature.com
Microbiome differential abundance analysis methods for two groups are well-established in
the literature. However, many microbiome studies involve more than two groups, sometimes …
the literature. However, many microbiome studies involve more than two groups, sometimes …
Estimated transmissibility and severity of novel SARS-CoV-2 Variant of Concern 202012/01 in England
A novel SARS-CoV-2 variant, VOC 202012/01, emerged in southeast England in November
2020 and is rapidly spreading towards fixation. Using a variety of statistical and dynamic …
2020 and is rapidly spreading towards fixation. Using a variety of statistical and dynamic …