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Transdermal skin delivery: predictions for humans from in vivo, ex vivo and animal models
The assessment of percutaneous permeation of molecules is one of the main steps in the
initial design and later in the evaluation of dermal or transdermal drug delivery systems. The …
initial design and later in the evaluation of dermal or transdermal drug delivery systems. The …
Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks
PD Darbre, PW Harvey - Journal of applied toxicology, 2008 - Wiley Online Library
This toxicology update reviews research over the past four years since publication in 2004 of
the first measurement of intact esters of p‐hydroxybenzoic acid (parabens) in human breast …
the first measurement of intact esters of p‐hydroxybenzoic acid (parabens) in human breast …
Lipid nanoparticles for improved topical application of drugs for skin diseases
Due to the lower risk of systemic side effects topical treatment of skin disease appears
favourable, yet the stratum corneum counteracts the penetration of xenobiotics into viable …
favourable, yet the stratum corneum counteracts the penetration of xenobiotics into viable …
UV filters: From sunscreens to human body and the environment
DL Giokas, A Salvador, A Chisvert - TrAC Trends in Analytical Chemistry, 2007 - Elsevier
Recognition of the harmful effects of ultraviolet (UV) radiation on the skin has triggered
development of organic chemicals (commonly referred as UV filters) that can absorb UV …
development of organic chemicals (commonly referred as UV filters) that can absorb UV …
In Vivo Methods for the Assessment of Topical Drug Bioavailability
This paper reviews some current methods for the in vivo assessment of local cutaneous
bioavailability in humans after topical drug application. After an introduction discussing the …
bioavailability in humans after topical drug application. After an introduction discussing the …
Photoprotection in changing times–UV filter efficacy and safety, sensitization processes and regulatory aspects
C Stiefel, W Schwack - International journal of cosmetic science, 2015 - Wiley Online Library
As excessive sun exposure is tightly associated with different pathological changes of the
skin, for example premature skin ageing or the development of skin cancer, an appropriate …
skin, for example premature skin ageing or the development of skin cancer, an appropriate …
[HTML][HTML] Increasing exposure to the UV filters octocrylene and 2-ethylhexyl salicylate in Germany from 1996 to 2020: Human biomonitoring in 24-h urine samples of the …
The UV filters octocrylene (OC) and 2-ethylhexyl salicylate (EHS) are commonly used in
sunscreens and frequently detected in environmental media. However, knowledge on …
sunscreens and frequently detected in environmental media. However, knowledge on …
In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen
A Mavon, C Miquel, O Lejeune, B Payre… - Skin pharmacology and …, 2006 - karger.com
Sunscreens, whose main function is to protect the skin against the harmful effects of solar
irradiation, should remain at the skin surface or impregnate the first layers of the stratum …
irradiation, should remain at the skin surface or impregnate the first layers of the stratum …
Finite and infinite dosing: Difficulties in measurements, evaluations and predictions
Due to the increased demand for reliable data regarding penetration into and permeation
across human skin, assessment of the absorption of xenobiotics has been gaining in …
across human skin, assessment of the absorption of xenobiotics has been gaining in …
Comparison of stratum corneum penetration and localization of a lipophilic model drug applied in an o/w microemulsion and an amphiphilic cream
A Teichmann, S Heuschkel, U Jacobi, G Presse… - European Journal of …, 2007 - Elsevier
Vehicle dependent effects on the penetration behavior of drugs following topical application
are well known from the literature. In this context, many reports concerning the enhancing …
are well known from the literature. In this context, many reports concerning the enhancing …