Lifestyle interventions in nonalcoholic fatty liver disease

ZM Younossi, S Zelber-Sagi, L Henry… - Nature Reviews …, 2023‏ - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a dynamic chronic liver disease that develops in
close association with metabolic irregularities. Between 2016 and 2019, the global …

Sarcopenia and frailty in decompensated cirrhosis

P Tandon, AJ Montano-Loza, JC Lai, S Dasarathy… - Journal of …, 2021‏ - Elsevier
In patients with decompensated cirrhosis, sarcopenia and frailty are prevalent. Although
several definitions exist for these terms, in the field of hepatology, sarcopenia has commonly …

Semaglutide 2· 4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trial

R Loomba, MF Abdelmalek, MJ Armstrong… - The lancet …, 2023‏ - thelancet.com
Background Patients with non-alcoholic steatohepatitis (NASH)-related cirrhosis are at high
risk of liver-related and all-cause morbidity and mortality. We investigated the efficacy and …

EASL Clinical Practice Guidelines on the management of hepatic encephalopathy

S Montagnese, PE Rautou, M Romero-Gómez… - Journal of …, 2022‏ - Elsevier
Summary The EASL Clinical Practice Guidelines (CPGs) on the management of hepatic
encephalopathy (HE) present evidence-based answers to a set of relevant questions (where …

AASLD practice guidance on primary sclerosing cholangitis and cholangiocarcinoma

CL Bowlus, L Arrivé, A Bergquist, M Deneau… - Hepatology, 2023‏ - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …

Malnutrition, frailty, and sarcopenia in patients with cirrhosis: 2021 practice guidance by the American Association for the Study of Liver Diseases

JC Lai, P Tandon, W Bernal, EB Tapper, U Ekong… - …, 2021‏ - Wiley Online Library
This is the first American Association for the Study of Liver Diseases (AASLD) practice
guidance on the management of malnutrition, frailty, and sarcopenia in patients with …

EASL Clinical Practice Guidelines on sclerosing cholangitis

O Chazouilleres, U Beuers, A Bergquist, TH Karlsen… - Journal of …, 2022‏ - Elsevier
Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

Diagnosis and treatment of alcohol-associated liver disease: a review

AK Singal, P Mathurin - Jama, 2021‏ - jamanetwork.com
Importance Alcohol-associated liver disease results in cirrhosis in approximately 10% to
20% of patients. In 2017, more than 2 million people had alcohol-associated cirrhosis in the …

Acute-on-chronic liver failure clinical guidelines

JS Bajaj, JG O'Leary, JC Lai, F Wong… - Official journal of the …, 2022‏ - journals.lww.com
In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging
as a major cause of mortality. These guidelines indicate the preferred approach to the …

Liver cirrhosis

P Ginès, A Krag, JG Abraldes, E Solà, N Fabrellas… - The Lancet, 2021‏ - thelancet.com
Cirrhosis is widely prevalent worldwide and can be a consequence of different causes, such
as obesity, non-alcoholic fatty liver disease, high alcohol consumption, hepatitis B or C …