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Development of dendritic form and function
The nervous system is populated by numerous types of neurons, each bearing a dendritic
arbor with a characteristic morphology. These type-specific features influence many aspects …
arbor with a characteristic morphology. These type-specific features influence many aspects …
The molecular basis of self-avoidance
S Lawrence Zipursky, WB Grueber - Annual review of …, 2013 - annualreviews.org
Self-avoidance, the tendency of neurites of the same cell to selectively avoid each other, is a
property of both vertebrate and invertebrate neurons. In Drosophila, self-avoidance is …
property of both vertebrate and invertebrate neurons. In Drosophila, self-avoidance is …
[HTML][HTML] Golgi outposts shape dendrite morphology by functioning as sites of acentrosomal microtubule nucleation in neurons
Microtubule nucleation is essential for proper establishment and maintenance of axons and
dendrites. Centrosomes, the primary site of nucleation in most cells, lose their function as …
dendrites. Centrosomes, the primary site of nucleation in most cells, lose their function as …
An extracellular adhesion molecule complex patterns dendritic branching and morphogenesis
Robust dendrite morphogenesis is a critical step in the development of reproducible neural
circuits. However, little is known about the extracellular cues that pattern complex dendrite …
circuits. However, little is known about the extracellular cues that pattern complex dendrite …
Phosphatidylserine externalization results from and causes neurite degeneration in Drosophila
Phagocytic clearance of degenerating dendrites or axons is critical for maintaining tissue
homeostasis and preventing neuroinflammation. Externalized phosphatidylserine (PS) has …
homeostasis and preventing neuroinflammation. Externalized phosphatidylserine (PS) has …
Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling
Lipid shuttling between neurons and glia contributes to the development, function, and
stress responses of the nervous system. To understand how a neuron acquires its lipid …
stress responses of the nervous system. To understand how a neuron acquires its lipid …
[HTML][HTML] Skin-derived cues control arborization of sensory dendrites in Caenorhabditis elegans
Sensory dendrites depend on cues from their environment to pattern their growth and direct
them toward their correct target tissues. Yet, little is known about dendrite-substrate …
them toward their correct target tissues. Yet, little is known about dendrite-substrate …
Sensory integration and neuromodulatory feedback facilitate Drosophila mechanonociceptive behavior
C Hu, M Petersen, N Hoyer, B Spitzweck… - Nature …, 2017 - nature.com
Nociception is an evolutionarily conserved mechanism to encode and process harmful
environmental stimuli. Like most animals, Drosophila melanogaster larvae respond to a …
environmental stimuli. Like most animals, Drosophila melanogaster larvae respond to a …
Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila
During developmental remodeling, neurites destined for pruning often degenerate on-site.
Physical injury also induces degeneration of neurites distal to the injury site. Prompt …
Physical injury also induces degeneration of neurites distal to the injury site. Prompt …
Intrinsic and extrinsic mechanisms of dendritic morphogenesis
The complex, branched morphology of dendrites is a cardinal feature of neurons and has
been used as a criterion for cell type identification since the beginning of neurobiology …
been used as a criterion for cell type identification since the beginning of neurobiology …