Endometriosis: Etiology, pathobiology, and therapeutic prospects

PTK Saunders, AW Horne - Cell, 2021 - cell.com
Endometriosis is a common condition associated with infertility that causes chronic pain in
many, but not all, women. It is defined by the presence of endometrial-like tissue outside the …

Pathophysiology, diagnosis, and management of endometriosis

AW Horne, SA Missmer - bmj, 2022 - bmj.com
Endometriosis affects approximately 190 million women and people assigned female at birth
worldwide. It is a chronic, inflammatory, gynecologic disease marked by the presence of …

Obesity and risk of female reproductive conditions: A Mendelian randomisation study

SS Venkatesh, T Ferreira, S Benonisdottir… - PLoS …, 2022 - journals.plos.org
Background Obesity is observationally associated with altered risk of many female
reproductive conditions. These include polycystic ovary syndrome (PCOS), abnormal uterine …

Pathogenesis of endometriosis: the origin of pain and subfertility

TM Gruber, S Mechsner - Cells, 2021 - mdpi.com
Endometriosis (EM) and adenomyosis (AM) are common conditions with pain and infertility
as the principal symptoms. The pathophysiology of pain in EM and AM comprises sensory …

Rational design ternary platinum based electrocatalysts for effective methanol oxidation reaction

H Tian, D Wu, J Li, J Luo, C Jia, Z Liu, W Huang… - Journal of Energy …, 2022 - Elsevier
Exploring effective, durable, and affordable electrocatalysts of methanol oxidation reaction
(MOR) is of vital significance for the industrial application of direct methanol fuel cells …

Epidemiology of adenomyosis

K Upson, SA Missmer - Seminars in reproductive medicine, 2020 - thieme-connect.com
Adenomyosis, characterized by the presence of endometrial glands and stroma within the
myometrium, can have a substantial impact on the quality of women's lives. Despite this, the …

Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities

IM McGrath, GW Montgomery… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Endometriosis remains a poorly understood disease, despite its high
prevalence and debilitating symptoms. The overlap in symptoms and the increased risk of …

Systematic review of Mendelian randomization studies on risk of cancer

G Markozannes, A Kanellopoulou, O Dimopoulou… - BMC medicine, 2022 - Springer
Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …

[HTML][HTML] A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes

S Mortlock, RI Corona, PF Kho, P Pharoah, JH Seo… - Cell Reports …, 2022 - cell.com
Endometriosis is associated with increased risk of epithelial ovarian cancers (EOCs). Using
data from large endometriosis and EOC genome-wide association meta-analyses, we …

A lifelong impact on endometriosis: pathophysiology and pharmacological treatment

LH Chen, WC Lo, HY Huang, HM Wu - International Journal of Molecular …, 2023 - mdpi.com
Endometriosis is a chronic inflammatory disease associated with bothersome symptoms in
premenopausal women and is complicated with long-term systemic impacts in the post …