Ventilator-associated pneumonia (VAP) is one of the most severe complications in patients
with traumatic brain injury (TBI) and is considered a risk factor for poor outcomes. However …

Allicin has been reported to play a biological role in human pathophysiological processes
via interaction with numerous signaling pathways and gene expression alteration. The …

Elevated circulating copper levels have been associated with chronic kidney disease (CKD),
kidney damage, and decline in kidney function. Using a two sample Mendelian …

Aims This study aimed to assess the effect of zinc supplementation, with or without other
antioxidants and trace elements, on clinical outcomes in patients with trauma. Methods A …

Background/Aims: Diabetes mellitus can exacerbate renal ischemia-reperfusion (I/R) injury
(RI/RI). The aim of the present study was to evaluate the protective effect of GSK-3β …

Background/Aims: Renal ischemia/reperfusion (I/R) injury (RI/RI) is a common complication
of diabetes, and it may be involved in altering intracellular calcium concentrations at its …

To determine the effects of zinc supplementation on clinical outcomes of patients with severe
head trauma, this double-blind clinical trial randomly allocated 100 patients with severe …

Background/Aims: Chelerythrine (CHE), a benzophenanthridine alkaloid, is a potent,
selective, and cell-permeable protein kinase C (PKC) inhibitor. The purpose of the present …

Background People with traumatic brain injury (TBI) are at high risk for infection and sepsis.
The aim of the study was to develop and validate an explainable machine learning (ML) …

The purpose of this research was to evaluate the protective effects of apocynin on renal
ischemia/reperfusion (I/R) injury (RI/RI) in rats. Rats preconditioned with apocynin were …