Advanced treatments based on immune system manipulation, gene transcription and
regulation, specific organ and cell targeting, and/or photon energy conversion have …

Engineering protein and peptide-based materials for drug delivery applications has gained
momentum due to their biochemical and biophysical properties over synthetic materials …

Matrix metalloproteinases (MMPs) are major extracellular enzymes involved in cancer
initiation, progression, and metastasis. MMPs are widely used as cancer biomarkers and …

In recent years, with the development of nanomaterials, the research of drug delivery
systems has become a new field of cancer therapy. Compared with conventional antitumor …

Immunotherapy is emerging as a powerful tool for combating many human diseases.
However, the application of this life-saving treatment in serious brain diseases, including …

Ferritin is an iron storage protein that plays a key role in iron homeostasis and anti-oxidation
of cells. Due to its unique architecture of 24 self-assembling subunits and hollow cavity …

Nature, in its wonders, presents and assembles the most intricate and delicate protein
structures and this remarkable phenomenon occurs in all kingdom and phyla of life. Of these …

Carcinoma-associated fibroblasts (CAFs) are found in many types of cancer and play an
important role in tumor growth and metastasis. Fibroblast-activation protein (FAP), which is …

The exploitation of nanosized materials for the delivery of therapeutic agents is already a
clinical reality and still holds unrealized potential for the treatment of a variety of diseases …

Abstract Human transferrin receptor 1 (CD71) guarantees iron supply by endocytosis upon
binding of iron-loaded transferrin and ferritin. Arenaviruses and the malaria parasite exploit …