Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …

Over the years, click and bioorthogonal reactions have been the subject of considerable
research efforts. These high-performance chemical reactions have been developed to meet …

Cancer is one of the major causes of death worldwide and its treatment remains very
challenging. The effectiveness of cancer therapy significantly depends upon tumour-specific …

The popularity of RAPTA-C in in vivo studies has steered the way for complexes of the type
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …

For the purpose of this review, active targeting in cancer research encompasses strategies
wherein a ligand for a cell surface receptor expressed on tumor cells is used to deliver a …

Current platinum-based drugs used in chemotherapy, like cisplatin and its derivatives, are
greatly limited due to side-effects and drug resistance. This has inspired the search for novel …

A biotin-guided platinumIV complex is highly cytotoxic against breast cancer cells but
hypotoxic against mammary epithelial cells. The mono-biotinylated PtIV complex is superior …

Cancer is characterized by abnormal cell differentiation in or on the part of the body. The
most commonly used chemotherapeutic drugs are developed to target rapidly dividing cells …

Cancer is the uncontrolled growth of cells in the body and is considered as one of the major
causes of death globally. There are several cytotoxic chemotherapeutic agents used to treat …

In this study, a CD44 and biotin receptors dual-targeted enzyme-sensitive hyaluronic acid
nanogel loading paclitaxel (PTX/Bio-NG) for targeting breast cancer was constructed …