Roughly one quarter of all genes code for integral membrane proteins that are inserted into
the plasma membrane of prokaryotes or the endoplasmic reticulum membrane of …

The signal recognition particle (SRP) and its receptor compose a universally conserved and
essential cellular machinery that couples the synthesis of nascent proteins to their proper …

This pioneering and celebrated work was the first, and remains the standard, account of the
economic history of the huge area conventionally known as West Africa. The book ranges …

Most eukaryotic multipass membrane proteins are inserted into the membrane of the
endoplasmic reticulum. Their transmembrane domains (TMDs) are thought to be inserted co …

Mitochondrial ribosomes (mitoribosomes) are tethered to the mitochondrial inner membrane
to facilitate the cotranslational membrane insertion of the synthesized proteins. We report …

About 25% to 30% of the bacterial proteins function in the cell envelope or outside of the
cell. These proteins are synthesized in the cytosol, and the vast majority is recognized as a …

Mitochondria are essential organelles of endosymbiotic origin that are responsible for
oxidative phosphorylation within eukaryotic cells. Independent evolution between species …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

Multipass membrane proteins contain two or more α-helical transmembrane domains
(TMDs) that span the lipid bilayer. They are inserted cotranslationally into the prokaryotic …

The vast majority of proteins trafficking across or into the bacterial cytoplasmic membrane
occur via the translocon. The translocon consists of the SecYEG complex that forms an …