The 2022 South America report of the Lancet Countdown on health and climate change: trust the science. Now that we know, we must act

SM Hartinger, M Yglesias-González… - The Lancet Regional …, 2023 - thelancet.com
Executive summary The health of South American populations is being severely impacted
by increasing climate change-driven environmental changes. Exacerbated by increased …

Live, attenuated, tetravalent Butantan–Dengue vaccine in children and adults

EG Kallás, MAT Cintra, JA Moreira… - … England Journal of …, 2024 - Mass Medical Soc
Abstract Background Butantan–Dengue Vaccine (Butantan-DV) is an investigational, single-
dose, live, attenuated, tetravalent vaccine against dengue disease, but data on its overall …

Dengue as a disease threatening global health: A narrative review focusing on Latin America and Brazil

CLS Lessa, KVS Hodel, MS Gonçalves… - Tropical Medicine and …, 2023 - mdpi.com
Arboviruses constitute the largest known group of viruses. These viruses are the etiological
agents of pathologies known as arboviruses, with dengue being one of the most prevalent …

Effects of boosting and waning in highly exposed populations on dengue epidemic dynamics

RA Aogo, JV Zambrana, N Sanchez, S Ojeda… - Science translational …, 2023 - science.org
Sequential infection with multiple dengue virus (DENV) serotypes is thought to induce
enduring protection against dengue disease. However, long-term antibody waning has been …

Efficacy and safety of Butantan-DV in participants aged 2–59 years through an extended follow-up: results from a double-blind, randomised, placebo-controlled, phase …

ML Nogueira, MAT Cintra, JA Moreira… - The Lancet Infectious …, 2024 - thelancet.com
Background A single-dose dengue vaccine that protects individuals across a wide age
range and regardless of dengue serostatus is an unmet need. We assessed the safety and …

Travel surveillance uncovers dengue virus dynamics and introductions in the Caribbean

E Taylor-Salmon, V Hill, LM Paul, RT Koch… - Nature …, 2024 - nature.com
Dengue is the most prevalent mosquito-borne viral disease in humans, and cases are
continuing to rise globally. In particular, islands in the Caribbean have experienced more …

Chemical biology and medicinal chemistry of RNA methyltransferases

TR Fischer, L Meidner, M Schwickert… - Nucleic Acids …, 2022 - academic.oup.com
RNA methyltransferases (MTases) are ubiquitous enzymes whose hitherto low profile in
medicinal chemistry, contrasts with the surging interest in RNA methylation, the arguably …

Trends in mosquito species distribution modeling: insights for vector surveillance and disease control

CA Lippi, SJ Mundis, R Sippy, JM Flenniken… - Parasites & …, 2023 - Springer
Species distribution modeling (SDM) has become an increasingly common approach to
explore questions about ecology, geography, outbreak risk, and global change as they …

Pandemic-associated mobility restrictions could cause increases in dengue virus transmission

SM Cavany, G España… - PLoS neglected …, 2021 - journals.plos.org
Background The COVID-19 pandemic has induced unprecedented reductions in human
mobility and social contacts throughout the world. Because dengue virus (DENV) …

[HTML][HTML] National dengue surveillance, Cambodia 2002–2020

C Yek, Y Li, AR Pacheco, C Lon, V Duong… - Bulletin of the World …, 2023 - ncbi.nlm.nih.gov
The global incidence of reported dengue has increased by tenfold over the last two
decades, from 505 430 cases in 2000 to 5.2 million in 2019. 1 To contain infection and …