Metallodrugs: an approach against invasion and metastasis in cancer treatment

MM González‐Ballesteros, C Mejía… - FEBS Open …, 2022 - Wiley Online Library
Cancer is a heterogeneous and multifactorial disease that causes high mortality throughout
the world; therefore, finding the most effective therapies is a major research challenge …

Trace minerals in human health: Iron, zinc, copper, manganese and fluorine

CS Silva, C Moutinho, A Ferreira da Vinha… - International Journal of …, 2019 - bdigital.ufp.pt
Trace elements exist in the environment in small amounts but play an essential part in
sustaining various physiological and metabolic processes occurring within living tissues, as …

Unlocking the biological potential of transition metal complexes with Thiosemicarbazone ligands: Insights from computational studies

D Khurana, B Kumar, J Devi, N Antil, RB Patil, K Singh… - Heliyon, 2024 - cell.com
In the previous study, the synthesis and characterization of 4-(3-fluorophenyl)-3-
thiosemicarbazide and benzaldehyde derivatives based thiosemicarbazone ligands and …

Metal-free methods for the generation of benzimidazoles and 2-aminobenzimidazoles

PJ Wanjari, N Saha, G Dubey, PV Bharatam - Tetrahedron, 2023 - Elsevier
Benzimidazoles, the important scaffold of various biologically important molecules, can be
synthesized using metal catalyzed and metal-free methodologies. Recently, metal-free …

Natural compounds as inhibitors of SARS-CoV-2 main protease (3CLpro): A molecular docking and simulation approach to combat COVID-19

MT Rehman, MF AlAjmi… - Current pharmaceutical …, 2021 - benthamdirect.com
Background: The emergence and dissemination of SARS-CoV-2 has caused high mortality
and enormous economic loss. Rapid development of new drug molecules is the need of …

[HTML][HTML] Zinc coordination compounds with benzimidazole derivatives: Synthesis, structure, antimicrobial activity and potential anticancer application

A Raducka, M Świątkowski, I Korona-Głowniak… - International Journal of …, 2022 - mdpi.com
Develo** new, smart drugs with the anticancer activity is crucial, especially for cancers,
which cause the highest mortality in humans. In this paper we describe a series of …

Metal complexes of benzimidazole-derived as potential anti-cancer agents: Synthesis, characterization, combined experimental and computational studies

VT Nguyen, TKC Huynh, GTT Ho… - Royal Society …, 2022 - royalsocietypublishing.org
In this study, a series of 14 Cu (II), Zn (II), Ni (II) and Ag (I) complexes containing bis-
benzimidazole derivatives were successfully designed and synthesized from 2-(1 H …

Novel series of nanosized mono-and homobi-nuclear metal complexes of sulfathiazole azo dye ligand: Synthesis, characterization, DNA-binding affinity, and …

AM Khedr, H El-Ghamry, MA Kassem, FA Saad… - Inorganic Chemistry …, 2019 - Elsevier
Novel five nanosized mono-and homobi-nuclear complexes of 4-(2, 4-dihydroxy-5-
formylphen-1-ylazo)-N-thiazol-2-yl-benzenesulfonamide (H 2 L) ligand were synthesized for …

Synthesis, DNA binding and biological evaluation of benzimidazole Schiff base ligands and their metal (ii) complexes

K Mahmood, Z Akhter, F Perveen, M Bibi, H Ismail… - RSC …, 2023 - pubs.rsc.org
Two novel benzimidazole ligands (E)-2-((4-(1H-benzo [d] imidazole-2-yl) phenylimino)
methyl)-6-bromo-4-chlorophenol (L1) and (E)-1-((4-(1H-benzo [d] imidazole-2-yl) …

[HTML][HTML] Evaluation of the anticancer activities of novel transition metal complexes with berenil and nitroimidazole

R Czarnomysy, D Radomska, A Muszyńska… - Molecules, 2020 - mdpi.com
Novel transition metal complexes (Au, Pd, Pt) with berenil and 2-(1-methyl-5-nitroimidazol-2-
yl) ethanol were obtained through two-step synthesis. The cytotoxicity assay against MCF-7 …