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[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …
have been used in many different biomedical fields including diagnosis, biosensing and …
Research progress of disulfide bond based tumor microenvironment targeted drug delivery system
W Ma, X Wang, D Zhang, X Mu - International Journal of …, 2024 - Taylor & Francis
Cancer poses a significant threat to human life and health. Chemotherapy is currently one of
the effective cancer treatments, but many chemotherapy drugs have cell toxicity, low …
the effective cancer treatments, but many chemotherapy drugs have cell toxicity, low …
[HTML][HTML] Exploring the Transformative Potential of Functionalized Mesoporous Silica in Enhancing Antioxidant Activity: A Comprehensive Review
Antioxidants are essential for reducing oxidative stress, protecting cells from damage, and
supporting overall well-being. Functionalized mesoporous silica materials have garnered …
supporting overall well-being. Functionalized mesoporous silica materials have garnered …
Guanidine functionalized porous SiO 2 as heterogeneous catalysts for microwave depolymerization of PET and PLA
Chemical recycling is an important strategy to tackle the growing global problem of plastic
waste pollution. The development of metal-free catalysts for depolymerization of plastics is …
waste pollution. The development of metal-free catalysts for depolymerization of plastics is …
[HTML][HTML] Virus-like silica nanoparticles improve permeability of macromolecules across the blood–brain barrier in vitro
The presence of the blood–brain barrier (BBB) limits the delivery of therapies into the brain.
There has been significant interest in overcoming the BBB for the effective delivery of …
There has been significant interest in overcoming the BBB for the effective delivery of …
[HTML][HTML] Establishing the Thermodynamic Cards of Dipine Models' Oxidative Metabolism on 21 Potential Elementary Steps
GB Shen, SH Gao, YW Jia, XQ Zhu, BC Qian - Molecules, 2024 - mdpi.com
Dipines are a type of important antihypertensive drug as L-calcium channel blockers, whose
core skeleton is the 1, 4-dihydropyridine structure. Since the dihydropyridine ring is a key …
core skeleton is the 1, 4-dihydropyridine structure. Since the dihydropyridine ring is a key …
Silica nanoparticles for brain cancer
Introduction Brain cancer is a debilitating disease with a poor survival rate. There are
significant challenges for effective treatment due to the presence of the blood–brain barrier …
significant challenges for effective treatment due to the presence of the blood–brain barrier …
Hollow mesoporous silica nanoparticles for drug formulation and delivery: opportunities for cancer therapy
H Guo, X Zhao, Y Duan, J Shi - Colloids and Surfaces B: Biointerfaces, 2025 - Elsevier
The advantages of large surface area, high volume ratio, good biocompatibility, and
controllable surface functionalization make hollow mesoporous silica nanoparticles …
controllable surface functionalization make hollow mesoporous silica nanoparticles …
Functionalization of Silica Nanoparticles for Tailored Interactions with Intestinal Cells and Chemical Modulation of Paracellular Permeability
The intestinal compartment confines the gut microbiome while enabling food passage and
absorption of active molecules. For the rational design of oral formulations aiming to …
absorption of active molecules. For the rational design of oral formulations aiming to …
[HTML][HTML] Harnessing silica nanoparticles grafted with ascorbic acid to alleviate oxidative stress and impaired brain activity in Rats
The brain has natural antioxidant defense systems, functioning through enzymes such as
superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase, which neutralize …
superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase, which neutralize …