Objectives This systematic review assesses dental implant survival, calculates the incidence
rate of osteoradionecrosis, and evaluates risk factors in irradiated head and neck cancer …

Background Osteoradionecrosis of the jaw (ORN) is an infrequent yet potentially devastating
complication of radiation therapy to the head and neck region. Treatment options include …

Purpose Hyperbaric oxygen (HBO) has been advocated in the prevention and treatment of
osteoradionecrosis (ORN) of the jaw after head and neck radiation therapy, but supporting …

Objective Very few studies have evaluated the efficacy of pentoxifylline and tocopherol
(PENT-E) in the management of medication-related osteonecrosis of the jaw (MRONJ) …

Patients undergoing radiotherapy for head and neck cancers are prone to a range of dental
complications, including mucositis, trismus, xerostomia, radiation caries and …

Objective The purpose of this study was to evaluate the healing benefit provided by the
antioxidant and antifibrotic properties of pentoxifylline–tocopherol or pentoxifylline …

ASCO Guidelines provide recommendations with comprehensive review and analyses of
the relevant literature for each recommendation, following the guideline development …

Radiation therapy is a valuable tool in the treatment of numerous malignancies but, in
certain cases, can also causes significant acute and chronic damage to noncancerous …

Bone-modifying agents (BMAs) are integral to managing patients with advanced cancer.
They improve quality of survival by reducing skeletal-related events, treating …

The fibroatrophic process has gained acceptance as a main mechanism of ORN. No gold
standard treatment or consensus guidelines exist, though a combination of therapeutic …