Heterogeneity and high versatility are the characteristic features of the cells of monocyte-
macrophage lineage. The mononuclear phagocyte system, derived from the bone marrow …

Plaque calcification develops by the inflammation-dependent mechanisms involved in
progression and regression of atherosclerosis. Macrophages can undergo two distinct …

Bidirectional cell–cell communication involving exosome-borne cargo such as miRNA has
emerged as a critical mechanism for wound healing. Unlike other shedding vesicles …

In skeletal muscle, new functions for vessels have recently emerged beyond oxygen and
nutrient supply, through the interactions that vascular cells establish with muscle stem cells …

At an injury site, efficient clearance of apoptotic cells by wound macrophages or
efferocytosis is a prerequisite for the timely resolution of inflammation. Emerging evidence …

Oncostatin M (OSM) and interleukin-31 (IL-31) are two cytokines belonging to the IL-6 family
which share a common signaling receptor subunit, the OSM receptor beta (OSMRβ). Both of …

Most of the leading causes of death, such as cardiovascular diseases, cancer, dementia,
neurodegenerative diseases, and many more, are associated with sterile inflammation …

Oncostatin M (OSM) is a pleiotropic cytokine involved in a variety of inflammatory responses
such as wound healing, liver regeneration, and bone remodeling. As a member of the …

Oncostatin M is a secreted cytokine involved in homeostasis and in diseases involving
chronic inflammation. It is a member of the gp130 family of cytokines that have pleiotropic …

Background A refractory wound is a typical complication of diabetes and is a common
outcome after surgery. Current approaches have difficulty in improving wound healing …