Unveiling microbial diversity: harnessing long-read sequencing technology

DP Agustinho, Y Fu, VK Menon, GA Metcalf… - Nature …, 2024 - nature.com
Long-read sequencing has recently transformed metagenomics, enhancing strain-level
pathogen characterization, enabling accurate and complete metagenome-assembled …

Sequencing and characterizing short tandem repeats in the human genome

HA Tanudisastro, IW Deveson, H Dashnow… - Nature Reviews …, 2024 - nature.com
Short tandem repeats (STRs) are highly polymorphic sequences throughout the human
genome that are composed of repeated copies of a 1–6-bp motif. Over 1 million variable …

A pangenome reference of 36 Chinese populations

Y Gao, X Yang, H Chen, X Tan, Z Yang, L Deng… - Nature, 2023 - nature.com
Human genomics is witnessing an ongoing paradigm shift from a single reference sequence
to a pangenome form, but populations of Asian ancestry are underrepresented. Here we …

Identification of errors in draft genome assemblies at single-nucleotide resolution for quality assessment and improvement

K Li, P Xu, J Wang, X Yi, Y Jiao - Nature Communications, 2023 - nature.com
Assembly of a high-quality genome is important for downstream comparative and functional
genomic studies. However, most tools for genome assembly assessment only give …

[HTML][HTML] A near-complete assembly of an Arabidopsis thaliana genome

X Hou, D Wang, Z Cheng, Y Wang, Y Jiao - Molecular plant, 2022 - cell.com
The genome sequence of Arabidopsis thaliana, a widely adopted model species, has
greatly expedited plant molecular biology research. Over 20 years after the first release of …

A near-complete cucumber reference genome assembly and Cucumber-DB, a multi-omics database

J Guan, H Miao, Z Zhang, S Dong, Q Zhou, X Liu… - Molecular Plant, 2024 - cell.com
Dear Editor, Cucumber (Cucumis sativus L.) is a key vegetable crop and an essential model
for genetics and genomics research in Cucurbitaceae, especially in studies on plant sex …

A proposed metric set for evaluation of genome assembly quality

P Wang, F Wang - Trends in Genetics, 2023 - cell.com
Quality control is essential for genome assemblies; however, a consensus has yet to be
reached on what metrics should be adopted for the evaluation of assembly quality. N50 is …

Genome assembly in the telomere-to-telomere era

H Li, R Durbin - Nature Reviews Genetics, 2024 - nature.com
Genome sequences largely determine the biology and encode the history of an organism,
and de novo assembly—the process of reconstructing the genome sequence of an organism …

North American pitseed goosefoot (Chenopodium berlandieri) is a genetic resource to improve Andean quinoa (C. quinoa)

PJ Maughan, DE Jarvis, E de la Cruz-Torres… - Scientific Reports, 2024 - nature.com
Pitseed goosefoot (Chenopodium berlandieri) is a free-living North American member of an
allotetraploid complex that includes the Andean pseudocereal quinoa (C. quinoa). Like …

W chromosome sequences of two bombycid moths provide an insight into the origin of Fem

J Lee, T Fujimoto, K Yamaguchi… - Molecular …, 2024 - Wiley Online Library
Fem is a W‐linked gene that encodes a piRNA precursor, and its product, Fem piRNA, is a
master factor of female determination in Bombyx mori. Fem has low similarity to any known …